Principal Clinical Scientist

About the Role

What if your years of clinical trial expertise could directly influence how AI reasons about medical evidence, regulatory submissions, and patient outcomes? We're looking for a Principal Clinical Scientist to bring senior-level rigour into the development of cutting-edge AI systems — ensuring these models understand clinical data the way the world's top regulatory scientists do.

What You'll Do

• Design and review clinical trial protocols that generate high-quality, regulator-ready datasets for AI training
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
• Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory expectations
• Provide expert, structured feedback that helps AI models reason more accurately about clinical trial data and outcomes
• Work independently and asynchronously — entirely on your own schedule

Who You Are

• Senior-level clinical scientist with hands-on experience designing clinical trial protocols for regulatory submission
• Deep expertise interpreting clinical data for regulatory agencies (FDA, EMA, or equivalent)
• Strong foundation in clinical research methodology, biostatistics, or translational science
• Naturally rigorous and detail-oriented — you hold data to the highest standard
• Clear and precise written communicator who can translate complex scientific concepts into structured feedback

Nice to Have

• Prior experience with data annotation, data quality assurance, or evaluation systems
• Familiarity with AI tools or machine learning workflows in a clinical or biomedical context
• Background in pharmacovigilance, outcomes research, or evidence-based medicine
• Experience working across multiple therapeutic areas or regulatory jurisdictions

Why Join Us

• Work directly on frontier AI systems that are reshaping clinical and biomedical research
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure and purpose of meaningful, expert-level work
• Influence how AI understands, evaluates, and communicates real-world clinical evidence at scale
• Collaborate with leading AI research teams and labs on genuinely novel challenges
• Potential for ongoing work and contract extension as new projects launch

Organization

Organization: Alignerr

Type

Type: Hourly Contract

Location

Location: Remote

Commitment

Commitment: 10–40 hours/week