Principal Clinical Scientist

About The Role

What if your career-long expertise in clinical trial design and regulatory science could directly shape how AI understands and evaluates clinical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows. You'll work with cutting-edge AI systems being developed by leading research labs — ensuring the clinical intelligence built into these models meets the standards expected in real-world regulatory environments. This is a fully remote, flexible contract role. No AI background needed — just deep command of clinical research and regulatory science.

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
• Evaluate AI-generated clinical analyses for scientific soundness and alignment with regulatory expectations (FDA, EMA, or equivalent)
• Provide expert, structured feedback that improves how AI models reason about clinical trial data, endpoints, and outcomes
• Help define quality standards for clinical data used across frontier AI research projects

Who You Are

• Senior-level experience designing clinical trial protocols for regulatory submission
• Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent bodies
• Strong background in clinical research methodology, biostatistics, translational science, or a closely related field
• Naturally rigorous and detail-oriented — you hold data and analysis to a high standard
• Able to communicate expert clinical judgment clearly in written feedback
• Comfortable working independently in a self-directed, asynchronous environment

Nice to Have

• Prior experience with data annotation, data quality evaluation, or AI model evaluation workflows
• Background in pharmacology, clinical pharmacokinetics, or outcomes research
• Experience working across multiple therapeutic areas or regulatory jurisdictions
• Familiarity with AI tools or structured evaluation platforms

Why Join Us

• Work directly on frontier AI systems making a real impact on clinical and biomedical research
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, expert-level work
• Influence how AI understands and evaluates real-world clinical evidence at a foundational level
• Potential for ongoing work and contract extension as new projects launch
• Global collaboration with world-class AI researchers and scientists