Principal Analytical Scientist (Automation)

About the role

Join our Quality Control team in Rensselaer, NY, supporting our IOPS organization. As a Principal Analytical Scientist, you will lead the design, implementation, and optimization of automated assay workflows across advanced laboratory platforms, while mentoring scientists and fostering a culture of technical growth and innovation.

Responsibilities

• Lead the design, implementation, and optimization of automated assay workflows across modern laboratory platforms, applying deep expertise in mass spectrometry, chromatography, bioassay, electrophoresis, and ELISA.
• Mentor and develop junior and mid-level scientists, building team capability in analytical science and laboratory automation.
• Set priorities, coordinate work, and track progress on analytical and automation initiatives against key milestones.
• Independently design and execute studies to evaluate emerging automation technologies and troubleshoot existing systems with limited supervision.
• Lead complex investigations into automated method performance, supporting verification activities and driving continuous improvement.
• Transfer automated workflows to QC and partner functions by developing training materials, transfer plans, and acceptance criteria.
• Engage cross-functional collaborators and equipment vendors to evaluate new technologies and assess their fit for QC applications.
• Prepare clear scientific reports, automation procedures, and SOPs; communicate findings, risks, and mitigation strategies to management and cross-functional teams.

Requirements

• 8+ years of industry experience in analytical development, laboratory automation, and QC method lifecycle management (or equivalent combination of education and experience).
• Demonstrated hands-on expertise in automated liquid handling platforms and associated software programming.
• Proficiency in scripting languages (Python, R, or VBA) for data analysis, workflow automation, or system integration.
• Deep knowledge of QC analytical techniques including mass spectrometry, chromatography, electrophoresis, bioassay, or ELISA.
• Proven ability to work independently, design scientifically sound studies from broad objectives, and drive projects to completion.

Qualifications

• PhD in Chemistry, Biochemistry, Biology, or a related field (preferred).
• Previous experience working in a cGMP or cGLP regulated environment (preferred).
• Familiarity with Cellario, Venus (Hamilton), or OneLab (Andrew+) automation platforms (preferred).
• Experience developing and executing technology transfer plans across QC or partner functions (preferred).

Skills

• Hands-on experience programming and optimizing automated liquid handling systems (e.g., Hamilton/Venus, Andrew+/OneLab, or Cellario).
• Strong troubleshooting skills across both analytical methods and automated instrumentation.
• Sound, independent decision-making and the ability to recommend experiments or solutions based on deep expertise in analytical science and automation.
• Leadership and mentorship abilities, leading by example in technical discussions and elevating the team's capabilities in automation strategy, method development, and process optimization.
• Ability to communicate complex automation concepts clearly to diverse audiences, both in written reports and in cross-functional settings.
• Proactive sharing of knowledge and taking pride in developing others through structured training and mentorship.
• Commitment to delivering on commitments safely, with high quality, and in compliance with regulatory expectations.

Benefits

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit here.

Pay

$92,200.00 - $150,600.00 annually

Schedule

Standard 1st shift, Monday-Friday, 8:00a-4:30p.