Precision Oncology SME

Prometheus Federal Services (PFS) is a trusted partner of federal health agencies. We are exploring adding a highly experienced Precision Oncology Subject Matter Expert (SME) to support a nationally significant federal precision medicine initiative focused on molecular testing, precision oncology, and evidence-based cancer care. In this role, the candidate will provide strategic clinical and scientific expertise to inform program direction, molecular testing guidance, implementation strategies, and stakeholder engagement activities.

Responsibilities

• Provide subject matter expertise in oncology, precision medicine, molecular diagnostics, and cancer genetics.
• Support precision oncology programs by translating emerging scientific evidence into actionable clinical or programmatic guidance.
• Apply and interpret NCCN Clinical Practice Guidelines and other evidence-based oncology care pathways to support clinical decision-making.
• Review, interpret, and advise on molecular testing strategies, biomarkers, assay platforms, and specimen selection across the cancer care continuum.
• Develop, maintain, or provide expert guidance on molecular testing recommendations across various cancer types and clinical scenarios.
• Provide specialized expertise in hematologic malignancies, including molecular testing approaches and biomarker interpretation.
• Collaborate with clinical, operational, and leadership stakeholders to support precision oncology initiatives and program objectives.
• Communicate complex scientific and clinical concepts effectively to diverse audiences, including clinicians, administrators, and executive leadership.
• Support enterprise-wide efforts to standardize molecular testing practices and precision oncology workflows.

Requirements

• MD or PhD in Oncology, Hematology/Oncology, Molecular Pathology, Genetics, Immunology, or a closely related field.
• Demonstrated expertise in oncology, precision medicine, molecular diagnostics, and cancer genetics.
• Strong knowledge of NCCN Clinical Practice Guidelines and evidence-based oncology care pathways.
• Experience supporting precision oncology programs and translating scientific evidence into clinical practice, policy, or program guidance.
• Expertise in hematologic malignancies and molecular testing applications for hematologic cancers.
• Knowledge of molecular assay platforms, biomarker testing, specimen requirements, and testing methodologies across the cancer care continuum.
• Experience developing, evaluating, or advising on molecular testing guidance and clinical recommendations.
• Excellent written, verbal, and presentation skills with the ability to communicate complex scientific concepts to technical and non-technical audiences.
• Ability to work in the U.S. indefinitely without sponsorship.
• Ability to obtain a public trust.

Preferred Qualifications

• Direct experience supporting VA, VHA, NPOP, or other national precision oncology programs.
• Experience supporting national molecular testing programs, multi-vendor testing models, or enterprise-level standardization initiatives.
• Familiarity with implementing molecular testing guidance across academic, community, federal, or integrated healthcare delivery settings.
• Experience working with multidisciplinary oncology teams, laboratory leaders, and healthcare executives to advance precision medicine programs.

Benefits

• Health, dental, and vision coverage.
• Flexible spending accounts.
• Disability and life insurance.
• Retirement plan.
• Paid time off.
• Other programs to support employees and their families.

Pay

Salary Range: $170,000 - $200,000