Postdoctoral Scientist – Synthetic & Medicinal Chemistry

About the role

This Postdoctoral Scientist position offers the opportunity to work at the interface of medicinal and process chemistry within a multidisciplinary team of chemists, analytical scientists, and engineers. The scientist will design and synthesize novel chemical targets, develop and apply new synthetic methodologies, and build deep insights into structure-function relationships that rapidly advance discovery and development efforts.

Responsibilities

• Working within a scientific team, conceptualize and execute new synthetic methodologies to rapidly screen and optimize relevant reactions.

• Purify starting materials, intermediates, and final compounds using modern separation techniques (e.g., flash chromatography, crystallization, preparative HPLC).

• Characterize reaction components, starting materials, and products by modern analytical techniques including NMR, HPLC, LC–MS, and related methods.

• Apply and develop single-electron chemistry approaches — photochemistry and/or electrochemistry — to enable new bond disconnections and methodology.

• Conduct chemical development using modern technologies such as continuous (flow) processing, automated/high-throughput reaction screening, and computational chemistry.

• Build, maintain, and troubleshoot laboratory instrumentation and equipment, contributing engineering insight to experimental design and scale-up.

• Review assay and analytical data, communicate results, and discuss the project impact of new findings.

• Author peer-reviewed external publications as a primary work output and present work in team and scientific meetings.

Requirements

• PhD in synthetic chemistry, organic chemistry, chemistry, biochemistry, chemical engineering, or a closely related field.

• Qualified applicants must be authorized to work in the United States on a full-time basis.

Qualifications

• Strong background in modern synthetic and/or medicinal chemistry with hands-on bench expertise.

• Proficiency with standard analytical and purification techniques, including NMR, HPLC, and LC–MS.

• Strongly Preferred: Demonstrated experience in photochemistry and/or electrochemistry, including reaction setup, optimization, and mechanistic understanding.

• Strongly Preferred: Engineering skills: strong engineering aptitude applied to chemistry — e.g., continuous/flow chemistry, reaction engineering and scale-up, process development, or design and integration of automated/instrumented systems.