Jobs · Analyst · Colorado

Postdoctoral Scientist – Synthetic & Medicinal Chemistry

BioSpace · Boulder, CO · 6 days ago
Analyst$58k–$123k/yrFull-time

Responsibilities

  • Working within a scientific team, conceptualize and execute new synthetic methodologies to rapidly screen and optimize relevant reactions.
  • Purify starting materials, intermediates, and final compounds using modern separation techniques (e.g., flash chromatography, crystallization, preparative HPLC).
  • Characterize reaction components, starting materials, and products by modern analytical techniques including NMR, HPLC, LC–MS, and related methods.
  • Apply and develop single-electron chemistry approaches — photochemistry and/or electrochemistry — to enable new bond disconnections and methodology.
  • Conduct chemical development using modern technologies such as continuous (flow) processing, automated/high-throughput reaction screening, and computational chemistry.
  • Build, maintain, and troubleshoot laboratory instrumentation and equipment, contributing engineering insight to experimental design and scale-up.
  • Review assay and analytical data, communicate results, and discuss the project impact of new findings.
  • Author peer-reviewed external publications as a primary work output and present work in team and scientific meetings.

Qualifications

  • PhD in synthetic chemistry, organic chemistry, chemistry, biochemistry, chemical engineering, or a closely related field.
  • Strong background in modern synthetic and/or medicinal chemistry with hands-on bench expertise.
  • Proficiency with standard analytical and purification techniques, including NMR, HPLC, and LC–MS.
  • Demonstrated experience or familiarity with single-electron chemistry: reaction setup, optimization, and mechanistic understanding.
  • Engineering skills: strong engineering aptitude applied to chemistry — e.g., continuous/flow chemistry, reaction engineering and scale-up, process development, or design and integration of automated/instrumented systems.
  • Experience or familiarity with data science, and with Python, R, or other coding languages.
  • Strong interest in creating and advancing new technologies in predictive and data-driven chemistry.
  • Demonstrated self-initiative, appropriate risk-taking, and a continual-learner mindset.
  • Demonstrated proficiency in scientific writing and publication in peer-reviewed journals, along with strong scientific presentation skills.
  • Excellent interpersonal, organizational, analytical, documentation, and multitasking skills, with the ability to prioritize and manage ambiguity in a fast-paced environment.
  • Demonstrated track record of creative, mechanism-based problem solving and effective teamwork.

Similar jobs

Postdoctoral Scientist

Eli Lilly and CompanySan Diego, CA· 2 days ago
Analyst$58k–$123k/yrapply on careers.lilly.com