Postdoctoral Scientist – Mitochondrial Biology

About the Lab

The Bomba-Warczak Laboratory at the University of Pennsylvania is recruiting creative, collaborative, and highly independent Postdoctoral Scientists to lead new research projects in mitochondrial biology. Our lab investigates how mitochondria are maintained and renewed in long-lived mammalian cells, with a particular interest in how organelle function is sustained over extended timescales in complex tissues. We integrate mouse models, quantitative biochemistry, stable-isotope tracing, and mass-spectrometry–based omics to understand the molecular mechanisms that govern mitochondrial maintenance, bioenergetics, and cellular resilience.

Learn more about the lab at bomba-warczaklab.com.

Projects

• Mechanisms of mitochondrial maintenance and renewal in long-lived cells
• Molecular coordination of mitochondrial gene expression and protein homeostasis
• Systems-level analysis of mitochondrial metabolism and proteome dynamics
• Mitochondrial function in complex mammalian tissues, including the nervous system

Required Qualifications

• PhD in Biology, Biochemistry, Cell Biology, Physiology, Neuroscience, or a related field
• Demonstrated research experience in mitochondrial biology
• At least one first-author primary research publication in a peer-reviewed journal
• Strong experimental and analytical skills in molecular or cellular biology
• Ability to independently design and execute experiments

Preferred Qualifications

• Experience working with mammalian systems and/or mouse models
• Exposure to mass spectrometry, proteomics, metabolomics or stable-isotope tracing or metabolic analysis
• Background in neuroscience or complex tissue physiology
• Computational/data analysis skills (R, Python, or similar)

Application

Applicants should submit a CV, cover letter, a PDF with relevant publication(s), and provide 3 contacts for references. In the cover letter, applicants should describe their research experience and indicate the experimental direction they would like to pursue in the lab.

Equal Employment Opportunity Statement

The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic characteristics), citizenship status, age, disability, veteran status or any class protected under applicable federal, state, or local law.