Postdoctoral Scholar - Penn State Biomedical Engineering

About the role

The Pritchard Lab in the Department of Biomedical Engineering at the Pennsylvania State University is seeking to fill a Postdoctoral Scholar position. The scholar will lead in vivo mouse studies at the interface of evolution, synthetic biology, and targeted therapy, supporting an NIH-funded program (5 year grant) that develops "selection gene drives," a regulated gene therapy that partners with standard-of-care targeted therapies to overcome drug resistance.

Responsibilities

• Design and execute efficacy and safety studies across cell line-derived xenograft (CDX), orthotopic, patient-derived xenograft (PDX), and immune-competent syngeneic models.
• Perform intravenous vector delivery.
• Conduct in vivo imaging (IVIS, micro-CT).
• Manage pharmacokinetic, pharmacodynamic, and toxicology cohorts.

Qualifications and Skills

• Ph.D. in Biomedical Engineering or a related scientific field (by time of appointment).
• Extensive hands‑on experience with mouse tumor models.
• Proficiency in in vivo techniques: intraperitoneal (IP), intravenous (IV), subcutaneous (SC) injections, and oral gavage.
• Strong background in modern molecular biology methods.

Benefits

Penn State provides a competitive benefits package for full‑time employees designed to support both personal and professional well‑being. For more detailed information, please visit the Benefits Page. (Note: For Postdoctoral benefits, please see the Postdoctoral Benefits page.)