Postdoctoral Researcher - Biophysics

Primary Responsibilities

• Supervise and independently execute studies related to the project described above
• Performing experiments, analyzing data, and disseminating results through presenting at conferences and writing manuscripts
• Work with an extensive network of world-class collaborators to study other aspects of GPCR signaling including biased agonism and allostery
• Expected to take an active role in one or more of these projects
• Plan, design and execute complex research studies, procedures and protocols
• Participate in discovery projects
• Cook up, coordinate research study activities; lead and manage projects
• Maintain organization, synthesis and analysis of data and findings
• Prepare scientific reports, outcome findings and scientific manuscripts
• Participate in meetings with principal investigator and research staff in which you will evaluate/interpret the validity of data, develop methodologies, and design and evaluate lab procedures

Qualifications

• Minimum Required Education: PhD
• Minimum Required Experience: 0 years
• PREFERRED EXPERIENCE: Expertise in GPCR pharmacology and signaling

Knowledge – Skills – Abilities

• Pharmacology, cell signaling, and/or biochemistry of GPCRs
• FRET/BRET-based cell signaling assays
• Mammalian cell culture and purification of functional membrane proteins embedded in a micelle or lipid (nanodisc) environment
• Site-directed mutagenesis for site-specific incorporation of spectroscopic probes (e.g. spin labels or fluorescent labels)
• Magnetic resonance, electron paramagnetic resonance
• Hardware/software interfacing
• Python, MATLAB, LabView, C/C++
• Excellent writing skills, as evidenced by first author publications

Physical Requirements

• Occasional exposure to dust, noise, temperature changes, or contact with water or other liquids
• Work requires occasionally lifting moderate weight materials, standing, or walking continuously
• Work is performed in an environmentally controlled environment
• Sensory Acuity Ability to detect and translate speech or other communication required. May occasionally require the ability to distinguish colors and perceive relative distances between objects