Postdoctoral Research Fellow - Jones Lab

Overview

The Jones Lab is developing next-generation covalent chemical biology with the objective of expanding the druggable proteome. We seek a highly motivated individual to join our collaborative research efforts as a POSTDOCTORAL RESEARCH FELLOW who will work on chemical biology projects directed towards the development of novel therapeutic modalities.

We are based at Dana-Farber Cancer Institute in Longwood Center, and we have access to state-of-the-art facilities for chemistry, biophysics, biochemistry, structural biology, and mass spectrometry.

Responsibilities

• Develop and apply biochemical, biophysical, and cellular assays to enable the development of chemical probes suitable for cellular and in vivo pharmacological validation
• Screens compounds; analyzes and interprets data
• Explore and elucidate molecular modes-of-action of chemical probes
• Maintain accurate lab records and documentation
• Contribute to publications and grant proposals
• Stay current with scientific advances in the fields of chemical biology and screening technologies, and apply emerging techniques and insights to their own research

Qualifications and Experience

• PhD degree in chemical biology or a related discipline
• Expert in protein preparation, biochemical assay development and compound screening
• Expert in chemical biology techniques used to assess interactions between proteins and small molecules
• Experience in cell-based assay development, compound screening and immunoblot
• Experience in chemoproteomics is desirable
• Excellent communication and presentation skills
• Evidence of consistent scientific innovation. Proven track record of publications in peer reviewed journals
• Able to work independently as well as in a collaborative team environment
• Excellent organizational and prioritization skills. Strong attention to detail
• Able to collect and analyze experimental data, prepare research publications, and communicate results

Pay

$72,000.00 - $76,385.00 per year