Postdoctoral Research Fellow (ikegami) Molecular Cardiovascular Biology

About the role

Located in the Molecular Cardiology Biology department at Cincinnati Children’s Hospital Medical Center (United States), this day‑shift, regular‑status postdoctoral fellowship (FTE 1, 40 hours/week) invites highly motivated candidates to investigate nuclear and chromatin organization and dynamics in development, homeostasis, and disease. Ongoing projects focus on nuclear mechanosensing, nuclear envelope damage and repair, and nuclear lamina–chromatin interactions in developmental and degenerative contexts. Applicants interested in extending these studies to cardiovascular, muscular, and nervous systems across development, disease, and aging are encouraged to apply. The lab uses a multidisciplinary approach integrating functional genomics, quantitative cell biology, mathematical modeling, mouse genetics and disease models, and bioinformatics. Cincinnati Children’s provides a strong research environment with ample opportunities for collaboration within and beyond the institution.

Responsibilities

• Develop critical thinking and data analysis skills; devise specific aims, plan long‑term projects, and design experiments to become an independent scientist.
• Design, execute, and record laboratory experiments; analyze data that may influence future patient care decisions.
• Research and improve current methods; evaluate innovative techniques.
• Ensure protocol and assay accuracy through regular quality and reproducibility checks.
• Implement findings within the Division/Department.
• Troubleshoot and correct erroneous results or problems with laboratory equipment.
• Discuss experimental insights with faculty and provide recommendations and analysis.
• Present research at laboratory meetings, journal clubs, seminars, and conferences.
• Develop skills to critically review and discuss data presented by others.
• Draft, write, and edit scientific reports, papers, journal articles, abstracts, and grant proposals.
• Assume progressively increasing responsibilities, including mentorship of research staff and fiscal administration.
• Maintain currency in the field through continuing education, literature review, and seminar attendance.
• Participate in intellectual discussions with the PI, faculty, trainees, and research staff.
• Seek feedback on career trajectory from the PI, mentoring committee, and other advisors.
• Attend required Cincinnati Children’s training sessions and ensure compliance with institutional policies (e.g., Infection Control, ORCRA).
• Perform other duties as assigned.

Requirements

PhD/MD or equivalent.

Qualifications

Prior experience in quantitative biology, functional genomics, or cardiovascular biology is beneficial but not required.

Skills

• Functional genomics
• Quantitative cell biology
• Mathematical modeling
• Mouse genetics and disease models
• Bioinformatics
• Critical thinking and data analysis
• Experimental design and long‑term project planning
• Troubleshooting laboratory equipment and correcting erroneous results
• Presenting research at meetings, journal clubs, seminars, and conferences
• Drafting, writing, and editing scientific reports, papers, and grant proposals
• Mentoring research staff and fiscal administration
• Continuing education and literature review

Schedule

Full‑time position, 40 hours per week (FTE 1).