Postdoctoral Research Associate - Wu Lab
About the Position
A Postdoctoral Research Fellow position is available to study molecular regulation of nucleotide metabolism across diverse human pathophysiological contexts. As a part of the newly established St. Jude Center for Pharmacogenomics, our laboratory aims to uncover fundamental mechanisms governing metabolic reprogramming and translate these discoveries into therapeutic strategies for human disease (Wu et al., Cell Metabolism, 2024, PMID: 38876105; Wu et al., Science, 2025, PMID: 41196949).
Research Approaches
We employ multidisciplinary approaches, including:
- CRISPR-based functional genomics
- Stable isotope tracing
- Metabolomics
- Molecular and cellular biology
- Biochemistry
- Mouse models
These approaches are used to investigate how nucleotide metabolism influences disease progression and treatment response.
Qualifications
- Recent doctoral degree (PhD, MD, or combined degrees)
- General background in molecular and cell biology, biochemistry, and genetics
- Track record of productivity
- Strong interest in cancer metabolism and immunometabolism
Mentorship and Career Development
Our laboratory is committed to creating a supportive, inclusive, and collaborative environment where trainees can thrive scientifically and professionally. Postdoctoral fellows will receive individualized mentorship, opportunities to develop independent research programs, and strong support for career advancement in academia.
About St. Jude
St. Jude Children's Research Hospital, located in Memphis, Tennessee, is a premier center for research and treatment of potentially fatal childhood diseases, including cancer and certain blood, genetic, and immunodeficiency disorders. The hospital's mission is to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. St. Jude is dedicated to providing unsurpassed patient care and to advancing the health of children through biomedical research.
Application Requirements
To apply please include a cover letter, CV and the names and contact information of three references.