Postdoctoral Research Associate - Molecular Oncology

About the role

The Li Lab in the Division of Molecular Oncology, Department of Oncology at St. Jude Children’s Research Hospital is seeking a highly motivated Postdoctoral Fellow to join our research team. The successful candidate will leverage cutting-edge, multidisciplinary research technologies in drug-controlled, degradable, oncogene-induced mouse tumor models to study dysregulated transcription in oncogenesis, tumor maintenance, and metastasis.

Responsibilities

• Develop an independent research project, including conception and planning, experiments, interpretation, writing, and publication
• Write grant proposals, give talks, and prepare scientific manuscripts under Dr. Li’s direct guidance
• Participate in scientific discussions, 1:1 meetings, and lab meetings
• Provide mentorship to summer students, rotation students, or interns when appropriate

Minimum Education and/or Training

PhD or MD/PhD

Special Skills, Knowledge, and Abilities

• Required skills: Passion for science and thirst for knowledge; strong laboratory skills in molecular biology and tissue culture; experience with animal husbandry is highly encouraged; collaborative personality, kind to others, and a team player
• Desired skills: Willingness to learn bioinformatics skills

About Li Lab

Li’s lab research focuses on understanding dysregulated transcriptional regulation of oncogenes within the three-dimensional (3D) chromatin niche in cancer. We conduct hypothesis-driven studies in three independent and complementary directions:

• Interrogate the complex function of the chromatin architecture maintenance in primary tumor by use of a unique acute protein degradation mouse model
• Deploy functional genomics to investigate non-coding cis-regulatory elements, RNA-binding proteins and related lncRNAs in regulating oncogene expression under the three-dimensional chromatin niche
• Develop novel tumor models, new methods, and advanced technologies to facilitate the above research of gene regulation

The homepage of Li Lab can be found at https://www.stjude.org/people/l/chunliang-li.html.

Recent selected publications from Li Lab (2023–now):

• https://pubmed.ncbi.nlm.nih.gov/42566532/
• https://pubmed.ncbi.nlm.nih.gov/42463942/
• https://pubmed.ncbi.nlm.nih.gov/42248454/
• https://pubmed.ncbi.nlm.nih.gov/40355969/
• https://pubmed.ncbi.nlm.nih.gov/40022213/
• https://pubmed.ncbi.nlm.nih.gov/38216972/
• https://pubmed.ncbi.nlm.nih.gov/37036970/
• https://pubmed.ncbi.nlm.nih.gov/36698211/
• https://pubmed.ncbi.nlm.nih.gov/38016946/

Benefits

• Access to shared resources and facilities led by expert scientists, coupled with cutting-edge technology
• Customized professional and career growth programs, including grant writing workshops, individual development plans, teaching and mentoring opportunities, non-research career advancement programs, and a professional development allowance
• Competitive salary starting at $72,500 a year, comprehensive benefits, and generous relocation assistance
• Vibrant postdoc community that supports a well-balanced life and fosters connections among postdocs from all backgrounds

Schedule

St. Jude Children’s Research Hospital is located in Memphis, Tennessee.