Postdoctoral Fellow - Skeletal Muscle Biology

About the role

We are seeking a highly motivated and creative Postdoctoral Fellow to join our multidisciplinary research program investigating the molecular mechanisms by which the circadian clock regulates skeletal muscle physiology, regeneration, metabolism, and muscular dystrophy.

Responsibilities

• Lead independent research projects while working collaboratively within a highly interactive laboratory environment.
• Design, execute, and interpret mechanistic studies addressing fundamental questions in circadian biology and skeletal muscle regeneration.
• Perform molecular, cellular, and in vivo experiments using genetically engineered mouse models and disease models of muscular dystrophy.
• Apply genomic and biochemical approaches to define transcriptional regulatory mechanisms controlling muscle stem cell function.
• Develop and evaluate pharmacological strategies targeting circadian pathways for muscle repair and disease treatment.
• Analyze large-scale datasets, including RNA-seq, ATAC-seq, ChIP-seq, and single-cell or single-nucleus sequencing data.
• Present research findings at laboratory meetings, scientific conferences, and national/international meetings.
• Prepare manuscripts for publication in leading scientific journals and contribute to grant applications.
• Mentor graduate students and junior trainees while fostering an inclusive and collaborative laboratory culture.

Requirements

• Ph.D. in Pharmacology, Molecular Biology, Cell Biology, Physiology, Genetics, Biochemistry, Biomedical Sciences, or a related discipline.
• Strong publication record demonstrating scientific productivity and independent research accomplishments.
• Expertise in at least several of the following areas: Skeletal muscle biology or stem cell biology, Gene regulation and transcriptional biology, Molecular pharmacology, Mouse genetics, Circadian biology, Signal transduction.
• Experience with standard biochemical, molecular and cellular biology techniques, including gene expression analysis, cloning, CRISPR-based approaches, protein biochemistry, and microscopy.
• Mastery of in vivo mouse studies is a plus.

Qualifications

• Commitment to reproducible and rigorous science.
• Ability to work productively with collaborators across diverse scientific disciplines, including molecular biology, genomics, physiology, computational biology, medicinal chemistry, and translational medicine.

Skills

• Strong interpersonal and communication skills.
• Enthusiasm for interdisciplinary and collaborative research.
• Willingness to mentor junior trainees and contribute to a positive laboratory culture.

Benefits

The City of Hope offers a comprehensive benefits package that includes:

• Health insurance
• Retirement plans
• Vacation and sick leave
• Flexible spending accounts
• Life and disability insurance
• Employee assistance programs

Pay

$34.25 – $37.82 per hour

Schedule

Full-time, 40 hours per week