Postdoctoral Fellow-Discovery Protein Science

About the role

The integrative Protein Generation and Protein Design groups within Discovery Protein Science are seeking a highly motivated and creative scientist to develop impactful platforms toward advancing new therapeutic hypotheses. In this vital role, you will apply interdisciplinary approaches to develop methodologies for autoantigen profiling, with implications for target identification and biomarker discovery.

Responsibilities

• Construct and validate protein libraries for autoantigen profiling
• Apply generated libraries to profile the binding of complex mixtures of antibodies
• Interact and collaborate with scientists cross-functionally, gaining broad exposure to the process of drug discovery
• Make novel discoveries that contribute to the broader field, disseminating scientific contributions through impactful publications and conference presentations

Requirements

• PhD in molecular biology, chemical biology, biochemistry, or related life sciences disciplines at the time of appointment
• Experience with protein library construction, mammalian cell culture, flow cytometry, and NGS analysis workflows is a plus
• Excellent critical thinking, organizational, and communication skills
• Passion to learn and work collaboratively within a large team of scientists with diverse technical and cultural backgrounds

Qualifications

• Independent design, execution, and interpretation of experiments and results, as exemplified by a solid publication record with first-author publication(s)
• Proven experience in sequence and structure-based construct design to improve protein expression and high-efficiency cloning methods

Benefits

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is $100,000. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible.