Postdoctoral Fellow, Chemistry Lewis Lab
About the role
The Lewis Lab in the Department of Chemistry at Indiana University is accepting applications for a Postdoctoral Fellow position. The position offers an opportunity to develop and apply cutting-edge protein engineering techniques to address fundamental challenges in synthetic chemistry and biocatalysis. The successful applicant will use a deep understanding of organic and organometallic chemistry, combined with state-of-the-art methods in generative protein design, directed evolution, next gen sequencing, and laboratory automation to develop B12-dependent enzymes or artificial metalloenzymes containing different organometallic cofactors for new chemical transformations.
Responsibilities
- Cloning and other molecular biology required for enzyme production and engineering
- Synthesis of substrates and product standards
- High throughput screening of enzyme libraries
- Application of computational protein design tools
- Careful documentation of all findings
- Formal research reports and presentations
- Participation in group equipment/facility maintenance
Qualifications
Required:
- PhD in any area of chemistry or biochemistry
- Extensive experience with either molecular biology OR synthetic chemistry
Preferred:
- Experience with both molecular biology and synthetic chemistry
- Familiarity with computational design tools
- Experience with organometallic catalysis/methodology development
- Experience with enzyme library generation and screening
About the lab
The Lewis Lab is a dynamic multidisciplinary laboratory environment. The successful applicant will play an integral role within our growing team of chemists, biochemists, and protein engineers and will emerge with a skill set that is equally relevant to academia and industry. Trainees receive regular guidance and feedback to ensure progress is made toward their career goals, whatever those may be. Trainees are also afforded the scheduling flexibility needed to maintain an appropriate work life balance.
Pay, schedule, and duration
The initial appointment will be for 12 months, with an additional 12-month extension available based on performance. A competitive salary along with a benefits package will be offered. Expected start date is October 1, 2026.
Application information
Interested candidates should submit a cover letter, CV, and contact information for three references to https://indiana.peopleadmin.com/postings/33690. Applications will be reviewed upon receipt. Best consideration date is July 21, 2026.
Questions regarding the position or application process can be directed to Prof. Lewis, Department of Chemistry, Indiana University, 800 E. Kirkwood Avenue, Bloomington, IN 47405, jcl3@iu.edu. For additional information visit https://lewis.lab.indiana.edu/.