Postdoctoral Fellow – Cancer Resistance Mechanisms and Biomarker Discovery
for each heading. Use - for any list of duties/requirements/benefits, and
for prose. Do NOT repeat job title as heading. Do NOT put Job ID/requisition numbers as headings. Remove boilerplate: cookie/navigation/legal/EEO/equal-opportunity/scam-warning, duplicated lines, application instructions. Preserve all substantive information; do not invent or summarize away detail. Include a section only when posting has real specific content for it — never emit heading followed by filler/placeholder text (e.g., "commensurate with experience", "not specified", "N/A", "varies", "TBD") and never create Pay/Schedule/Benefits sections unless posting actually states them.
We need to parse the posting.
Content:
- Intro paragraph: "Join the forefront of groundbreaking research at City of Hope where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research."
- Then description of lab: "We are seeking a highly motivated Postdoctoral Fellow to join the laboratory of Andrea H. Bild, PhD, Professor in the Department of Medical Oncology & Therapeutics Research and leader in translational systems biology and precision oncology. The Bild Laboratory investigates the molecular mechanisms that drive therapeutic response and resistance in cancer. Our multidisciplinary research integrates molecular biology, pharmacology, genomics, computational biology, and translational oncology to identify actionable signaling networks and develop predictive biomarkers that improve patient outcomes."
- Then "The successful candidate will contribute to projects focused on understanding and targeting resistant cancer traits using advanced experimental and systems-level approaches."
- Then "As a successful candidate you will:" followed by bullet list of duties (starting with "Lead independent studies..." etc). Those are responsibilities.
- Then "Your qualifications should include:" followed by list of qualifications (PhD etc). Then "Preferred qualifications:" list.
- Then "City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location." This is pay info. So we have pay specifics: based on work experience, qualifications, work location. That's specific enough? It says pay is based on criteria, not actual numbers. The instruction: never create Pay/Schedule/Benefits sections unless posting actually states them. It does state pay criteria, so we can include a Pay section with that info. However we must avoid filler like "commensurate with experience". This is similar but it's specific criteria. So we can include Pay section.
- Then "City of Hope is an equal opportunity employer." That's EEO boilerplate, should be removed.
- Then "To learn more about our Comprehensive Benefits, please CLICK HERE." That's a benefits reference but no detail. It says to learn more about benefits, but no actual benefits listed. According to rule: never create Benefits section unless posting actually states them. It only mentions benefits link but no detail. So we should not create a Benefits section.
- Then "#PD" maybe a tag, ignore.
- No schedule info.
Thus sections we can have: About the role (intro + lab description), Responsibilities (the bullet list after "As a successful candidate you will:"), Requirements (maybe the "Your qualifications should include:" list), Preferred qualifications could be part of Requirements or separate Skills? The instruction: Use headings for section headings (e.g. About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule). It lists Qualifications and Skills separate. We have qualifications (required) and preferred qualifications. Could treat required as Requirements, preferred as Skills? Or we could combine required and preferred under Requirements. But we have to avoid thin sections. Perhaps we can have Requirements (required) and Skills (preferred). Or we could have Requirements (required) and Preferred Qualifications as a separate section? The list of allowed headings includes Qualifications and Skills. It does not list "Preferred Qualifications". So we could put required under Requirements, preferred under Skills. That seems reasonable.
Pay section: we have pay criteria.
Thus sections: About the role, Responsibilities, Requirements, Skills, Pay.
We need to use
for each heading. Use - for any list of duties/requirements/benefits. Use
for prose.
We must not repeat job title as heading. The job title is Postdoctoral Fellow; we won't use that.
We must not include Job ID/requisition numbers.
We must preserve all substantive information; do not invent or summarize away detail.
We need to extract the prose for About the role: combine the intro paragraph and lab description and the sentence about successful candidate will contribute to projects... That is part of responsibilities? Actually that sentence is more about role. Could be part of About the role. Let's include it.
Thus About the role prose: "Join the forefront of groundbreaking research at City of Hope where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research. We are seeking a highly motivated Postdoctoral Fellow to join the laboratory of Andrea H. Bild, PhD, Professor in the Department of Medical Oncology & Therapeutics Research and leader in translational systems biology and precision oncology. The Bild Laboratory investigates the molecular mechanisms that drive therapeutic response and resistance in cancer. Our multidisciplinary research integrates molecular biology, pharmacology, genomics, computational biology, and translational oncology to identify actionable signaling networks and develop predictive biomarkers that improve patient outcomes. The successful candidate will contribute to projects focused on understanding and targeting resistant cancer traits using advanced experimental and systems-level approaches."
That seems fine.
Responsibilities: bullet list after "As a successful candidate you will:" includes:
- Lead independent studies investigating the molecular, cellular, epigenetic, and signaling mechanisms underlying intrinsic and acquired treatment resistance in solid tumors.
- Design and perform molecular, cellular, and pharmacologic experiments using cell-based, ex vivo, and patient-derived cancer models.
- Characterize oncogenic pathways, adaptive cellular states, and resistance-associated vulnerabilities to identify promising therapeutic targets and combinations.
- Integrate molecular, genomic, transcriptomic, epigenetic, and phenotypic data to uncover actionable drivers of treatment response and resistance.
- Develop and validate predictive biomarkers of therapeutic outcomes, including blood-based genetic and epigenetic assays and methylation-based tests.
- Advance translational studies that support precision oncology clinical trials and biomarker-guided treatment strategies using City of Hope’s patient specimens, genomic technologies, single-cell platforms, computational resources, and clinical collaborations.
- Collaborate with basic, computational, and clinical investigators and present findings at laboratory meetings, institutional seminars, and scientific conferences.
- Prepare manuscripts for publication in high-impact journals and contribute to grant applications.
We need to put each as
- inside
.
Requirements: list after "Your qualifications should include:" includes:
- PhD, MD/PhD, PharmD, or equivalent doctoral degree in Cancer Biology, Pharmacology, Molecular Biology, Systems Biology, Bioengineering, Computational Biology, or a related discipline.
- Strong background in cancer biology and molecular signaling.
- Experience with one or more of the following:
- Cell culture and functional assays
- Molecular biology techniques
- CRISPR or genetic perturbation approaches
- Genomics, transcriptomics, or single-cell technologies
- Pharmacology and drug response studies
- Bioinformatics or computational analysis
- Excellent written and verbal communication skills.
- Demonstrated publication record in peer-reviewed journals.
We need to format as list. The inner list could be nested but spec says use - for any list of duties/requirements/benefits. It doesn't forbid nested lists. We can keep as top-level items, with the "Experience with one or more of the following:" as a
- containing a sublist? Might be okay. Simpler: treat each bullet as a top-level
- , and for the experience bullet we can include the sub-items as separate
- under a nested
. That preserves detail.
Skills: preferred qualifications list:
- Experience studying therapeutic resistance in cancer.
- Familiarity with signaling pathway analysis and biomarker development.
- Experience with systems biology approaches.
- Knowledge of translational oncology and precision medicine strategies.
- Interest in interdisciplinary collaborations bridging laboratory and clinical research.
We'll put each as - .
Pay: "City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location." We'll put as
.
We must not include Benefits section.
We must not include Schedule.
We must not include EEO line.
We must not include "To learn more about our Comprehensive Benefits, please CLICK HERE."
We must not include "#PD".
Now output HTML fragment only.
Let's craft:
About the role
Join the forefront of groundbreaking research at City of Hope where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research. We are seeking a highly motivated Postdoctoral Fellow to join the laboratory of Andrea H. Bild, PhD, Professor in the Department of Medical Oncology & Therapeutics Research and leader in translational systems biology and precision oncology. The Bild Laboratory investigates the molecular mechanisms that drive therapeutic response and resistance in cancer. Our multidisciplinary research integrates molecular biology, pharmacology, genomics, computational biology, and translational oncology to identify actionable signaling networks and develop predictive biomarkers that improve patient outcomes. The successful candidate will contribute to projects focused on understanding and targeting resistant cancer traits using advanced experimental and systems-level approaches.
Responsibilities
- Lead independent studies investigating the molecular, cellular, epigenetic, and signaling mechanisms underlying intrinsic and acquired treatment resistance in solid tumors.
- Design and perform molecular, cellular, and pharmacologic experiments using cell-based, ex vivo, and patient-derived cancer models.
- Characterize oncogenic pathways, adaptive cellular states, and resistance-associated vulnerabilities to identify promising therapeutic targets and combinations.
- Integrate molecular, genomic, transcriptomic, epigenetic, and phenotypic data to uncover actionable drivers of treatment response and resistance.
- Develop and validate predictive biomarkers of therapeutic outcomes, including blood-based genetic and epigenetic assays and methylation-based tests.
- Advance translational studies that support precision oncology clinical trials and biomarker-guided treatment strategies using City of Hope’s patient specimens, genomic technologies, single-cell platforms, computational resources, and clinical collaborations.
- Collaborate with basic, computational, and clinical investigators and present findings at laboratory meetings, institutional seminars, and scientific conferences.
- Prepare manuscripts for publication in high-impact journals and contribute to grant applications.
Requirements
- PhD, MD/PhD, PharmD, or equivalent doctoral degree in Cancer Biology, Pharmacology, Molecular Biology, Systems Biology, Bioengineering, Computational Biology, or a related discipline.
- Strong background in cancer biology and molecular signaling.
- Experience with one or more of the following:
- Cell culture and functional assays
- Molecular biology techniques
- CRISPR or genetic perturbation approaches
- Genomics, transcriptomics, or single-cell technologies
- Pharmacology and drug response studies
- Bioinformatics or computational analysis
- Excellent written and verbal communication skills.
- Demonstrated publication record in peer-reviewed journals.
Skills
- Experience studying therapeutic resistance in cancer.
- F
for prose. Do NOT repeat job title as heading. Do NOT put Job ID/requisition numbers as headings. Remove boilerplate: cookie/navigation/legal/EEO/equal-opportunity/scam-warning, duplicated lines, application instructions. Preserve all substantive information; do not invent or summarize away detail. Include a section only when posting has real specific content for it — never emit heading followed by filler/placeholder text (e.g., "commensurate with experience", "not specified", "N/A", "varies", "TBD") and never create Pay/Schedule/Benefits sections unless posting actually states them. We need to parse the posting. Content: - Intro paragraph: "Join the forefront of groundbreaking research at City of Hope where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research." - Then description of lab: "We are seeking a highly motivated Postdoctoral Fellow to join the laboratory of Andrea H. Bild, PhD, Professor in the Department of Medical Oncology & Therapeutics Research and leader in translational systems biology and precision oncology. The Bild Laboratory investigates the molecular mechanisms that drive therapeutic response and resistance in cancer. Our multidisciplinary research integrates molecular biology, pharmacology, genomics, computational biology, and translational oncology to identify actionable signaling networks and develop predictive biomarkers that improve patient outcomes." - Then "The successful candidate will contribute to projects focused on understanding and targeting resistant cancer traits using advanced experimental and systems-level approaches." - Then "As a successful candidate you will:" followed by bullet list of duties (starting with "Lead independent studies..." etc). Those are responsibilities. - Then "Your qualifications should include:" followed by list of qualifications (PhD etc). Then "Preferred qualifications:" list. - Then "City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location." This is pay info. So we have pay specifics: based on work experience, qualifications, work location. That's specific enough? It says pay is based on criteria, not actual numbers. The instruction: never create Pay/Schedule/Benefits sections unless posting actually states them. It does state pay criteria, so we can include a Pay section with that info. However we must avoid filler like "commensurate with experience". This is similar but it's specific criteria. So we can include Pay section. - Then "City of Hope is an equal opportunity employer." That's EEO boilerplate, should be removed. - Then "To learn more about our Comprehensive Benefits, please CLICK HERE." That's a benefits reference but no detail. It says to learn more about benefits, but no actual benefits listed. According to rule: never create Benefits section unless posting actually states them. It only mentions benefits link but no detail. So we should not create a Benefits section. - Then "#PD" maybe a tag, ignore. - No schedule info. Thus sections we can have: About the role (intro + lab description), Responsibilities (the bullet list after "As a successful candidate you will:"), Requirements (maybe the "Your qualifications should include:" list), Preferred qualifications could be part of Requirements or separate Skills? The instruction: Use headings for section headings (e.g. About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule). It lists Qualifications and Skills separate. We have qualifications (required) and preferred qualifications. Could treat required as Requirements, preferred as Skills? Or we could combine required and preferred under Requirements. But we have to avoid thin sections. Perhaps we can have Requirements (required) and Skills (preferred). Or we could have Requirements (required) and Preferred Qualifications as a separate section? The list of allowed headings includes Qualifications and Skills. It does not list "Preferred Qualifications". So we could put required under Requirements, preferred under Skills. That seems reasonable. Pay section: we have pay criteria. Thus sections: About the role, Responsibilities, Requirements, Skills, Pay. We need to use
for each heading. Use - for any list of duties/requirements/benefits. Use
for prose.
We must not repeat job title as heading. The job title is Postdoctoral Fellow; we won't use that.
We must not include Job ID/requisition numbers.
We must preserve all substantive information; do not invent or summarize away detail.
We need to extract the prose for About the role: combine the intro paragraph and lab description and the sentence about successful candidate will contribute to projects... That is part of responsibilities? Actually that sentence is more about role. Could be part of About the role. Let's include it.
Thus About the role prose: "Join the forefront of groundbreaking research at City of Hope where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research. We are seeking a highly motivated Postdoctoral Fellow to join the laboratory of Andrea H. Bild, PhD, Professor in the Department of Medical Oncology & Therapeutics Research and leader in translational systems biology and precision oncology. The Bild Laboratory investigates the molecular mechanisms that drive therapeutic response and resistance in cancer. Our multidisciplinary research integrates molecular biology, pharmacology, genomics, computational biology, and translational oncology to identify actionable signaling networks and develop predictive biomarkers that improve patient outcomes. The successful candidate will contribute to projects focused on understanding and targeting resistant cancer traits using advanced experimental and systems-level approaches."
That seems fine.
Responsibilities: bullet list after "As a successful candidate you will:" includes:
- Lead independent studies investigating the molecular, cellular, epigenetic, and signaling mechanisms underlying intrinsic and acquired treatment resistance in solid tumors.
- Design and perform molecular, cellular, and pharmacologic experiments using cell-based, ex vivo, and patient-derived cancer models.
- Characterize oncogenic pathways, adaptive cellular states, and resistance-associated vulnerabilities to identify promising therapeutic targets and combinations.
- Integrate molecular, genomic, transcriptomic, epigenetic, and phenotypic data to uncover actionable drivers of treatment response and resistance.
- Develop and validate predictive biomarkers of therapeutic outcomes, including blood-based genetic and epigenetic assays and methylation-based tests.
- Advance translational studies that support precision oncology clinical trials and biomarker-guided treatment strategies using City of Hope’s patient specimens, genomic technologies, single-cell platforms, computational resources, and clinical collaborations.
- Collaborate with basic, computational, and clinical investigators and present findings at laboratory meetings, institutional seminars, and scientific conferences.
- Prepare manuscripts for publication in high-impact journals and contribute to grant applications.
We need to put each as
- inside
.
Requirements: list after "Your qualifications should include:" includes:
- PhD, MD/PhD, PharmD, or equivalent doctoral degree in Cancer Biology, Pharmacology, Molecular Biology, Systems Biology, Bioengineering, Computational Biology, or a related discipline.
- Strong background in cancer biology and molecular signaling.
- Experience with one or more of the following:
- Cell culture and functional assays
- Molecular biology techniques
- CRISPR or genetic perturbation approaches
- Genomics, transcriptomics, or single-cell technologies
- Pharmacology and drug response studies
- Bioinformatics or computational analysis
- Excellent written and verbal communication skills.
- Demonstrated publication record in peer-reviewed journals.
We need to format as list. The inner list could be nested but spec says use - for any list of duties/requirements/benefits. It doesn't forbid nested lists. We can keep as top-level items, with the "Experience with one or more of the following:" as a
- containing a sublist? Might be okay. Simpler: treat each bullet as a top-level
- , and for the experience bullet we can include the sub-items as separate
- under a nested
. That preserves detail.
Skills: preferred qualifications list:
- Experience studying therapeutic resistance in cancer.
- Familiarity with signaling pathway analysis and biomarker development.
- Experience with systems biology approaches.
- Knowledge of translational oncology and precision medicine strategies.
- Interest in interdisciplinary collaborations bridging laboratory and clinical research.
We'll put each as - .
Pay: "City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location." We'll put as
.
We must not include Benefits section.
We must not include Schedule.
We must not include EEO line.
We must not include "To learn more about our Comprehensive Benefits, please CLICK HERE."
We must not include "#PD".
Now output HTML fragment only.
Let's craft:
About the role
Join the forefront of groundbreaking research at City of Hope where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research. We are seeking a highly motivated Postdoctoral Fellow to join the laboratory of Andrea H. Bild, PhD, Professor in the Department of Medical Oncology & Therapeutics Research and leader in translational systems biology and precision oncology. The Bild Laboratory investigates the molecular mechanisms that drive therapeutic response and resistance in cancer. Our multidisciplinary research integrates molecular biology, pharmacology, genomics, computational biology, and translational oncology to identify actionable signaling networks and develop predictive biomarkers that improve patient outcomes. The successful candidate will contribute to projects focused on understanding and targeting resistant cancer traits using advanced experimental and systems-level approaches.
Responsibilities
- Lead independent studies investigating the molecular, cellular, epigenetic, and signaling mechanisms underlying intrinsic and acquired treatment resistance in solid tumors.
- Design and perform molecular, cellular, and pharmacologic experiments using cell-based, ex vivo, and patient-derived cancer models.
- Characterize oncogenic pathways, adaptive cellular states, and resistance-associated vulnerabilities to identify promising therapeutic targets and combinations.
- Integrate molecular, genomic, transcriptomic, epigenetic, and phenotypic data to uncover actionable drivers of treatment response and resistance.
- Develop and validate predictive biomarkers of therapeutic outcomes, including blood-based genetic and epigenetic assays and methylation-based tests.
- Advance translational studies that support precision oncology clinical trials and biomarker-guided treatment strategies using City of Hope’s patient specimens, genomic technologies, single-cell platforms, computational resources, and clinical collaborations.
- Collaborate with basic, computational, and clinical investigators and present findings at laboratory meetings, institutional seminars, and scientific conferences.
- Prepare manuscripts for publication in high-impact journals and contribute to grant applications.
Requirements
- PhD, MD/PhD, PharmD, or equivalent doctoral degree in Cancer Biology, Pharmacology, Molecular Biology, Systems Biology, Bioengineering, Computational Biology, or a related discipline.
- Strong background in cancer biology and molecular signaling.
- Experience with one or more of the following:
- Cell culture and functional assays
- Molecular biology techniques
- CRISPR or genetic perturbation approaches
- Genomics, transcriptomics, or single-cell technologies
- Pharmacology and drug response studies
- Bioinformatics or computational analysis
- Excellent written and verbal communication skills.
- Demonstrated publication record in peer-reviewed journals.
Skills
- Experience studying therapeutic resistance in cancer.
- F
for prose. We must not repeat job title as heading. The job title is Postdoctoral Fellow; we won't use that. We must not include Job ID/requisition numbers. We must preserve all substantive information; do not invent or summarize away detail. We need to extract the prose for About the role: combine the intro paragraph and lab description and the sentence about successful candidate will contribute to projects... That is part of responsibilities? Actually that sentence is more about role. Could be part of About the role. Let's include it. Thus About the role prose: "Join the forefront of groundbreaking research at City of Hope where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research. We are seeking a highly motivated Postdoctoral Fellow to join the laboratory of Andrea H. Bild, PhD, Professor in the Department of Medical Oncology & Therapeutics Research and leader in translational systems biology and precision oncology. The Bild Laboratory investigates the molecular mechanisms that drive therapeutic response and resistance in cancer. Our multidisciplinary research integrates molecular biology, pharmacology, genomics, computational biology, and translational oncology to identify actionable signaling networks and develop predictive biomarkers that improve patient outcomes. The successful candidate will contribute to projects focused on understanding and targeting resistant cancer traits using advanced experimental and systems-level approaches." That seems fine. Responsibilities: bullet list after "As a successful candidate you will:" includes: - Lead independent studies investigating the molecular, cellular, epigenetic, and signaling mechanisms underlying intrinsic and acquired treatment resistance in solid tumors. - Design and perform molecular, cellular, and pharmacologic experiments using cell-based, ex vivo, and patient-derived cancer models. - Characterize oncogenic pathways, adaptive cellular states, and resistance-associated vulnerabilities to identify promising therapeutic targets and combinations. - Integrate molecular, genomic, transcriptomic, epigenetic, and phenotypic data to uncover actionable drivers of treatment response and resistance. - Develop and validate predictive biomarkers of therapeutic outcomes, including blood-based genetic and epigenetic assays and methylation-based tests. - Advance translational studies that support precision oncology clinical trials and biomarker-guided treatment strategies using City of Hope’s patient specimens, genomic technologies, single-cell platforms, computational resources, and clinical collaborations. - Collaborate with basic, computational, and clinical investigators and present findings at laboratory meetings, institutional seminars, and scientific conferences. - Prepare manuscripts for publication in high-impact journals and contribute to grant applications. We need to put each as
- .
Requirements: list after "Your qualifications should include:" includes:
- PhD, MD/PhD, PharmD, or equivalent doctoral degree in Cancer Biology, Pharmacology, Molecular Biology, Systems Biology, Bioengineering, Computational Biology, or a related discipline.
- Strong background in cancer biology and molecular signaling.
- Experience with one or more of the following:
- Cell culture and functional assays
- Molecular biology techniques
- CRISPR or genetic perturbation approaches
- Genomics, transcriptomics, or single-cell technologies
- Pharmacology and drug response studies
- Bioinformatics or computational analysis
- Excellent written and verbal communication skills.
- Demonstrated publication record in peer-reviewed journals.
We need to format as list. The inner list could be nested
- for any list of duties/requirements/benefits. It doesn't forbid nested lists. We can keep as top-level items, with the "Experience with one or more of the following:" as a
- containing a sublist? Might be okay. Simpler: treat each bullet as a top-level
- , and for the experience bullet we can include the sub-items as separate
- under a nested
- . That preserves detail.
Skills: preferred qualifications list:
- Experience studying therapeutic resistance in cancer.
- Familiarity with signaling pathway analysis and biomarker development.
- Experience with systems biology approaches.
- Knowledge of translational oncology and precision medicine strategies.
- Interest in interdisciplinary collaborations bridging laboratory and clinical research.
We'll put each as
- .
Pay: "City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location." We'll put as
. We must not include Benefits section. We must not include Schedule. We must not include EEO line. We must not include "To learn more about our Comprehensive Benefits, please CLICK HERE." We must not include "#PD". Now output HTML fragment only. Let's craft:
About the role
Join the forefront of groundbreaking research at City of Hope where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research. We are seeking a highly motivated Postdoctoral Fellow to join the laboratory of Andrea H. Bild, PhD, Professor in the Department of Medical Oncology & Therapeutics Research and leader in translational systems biology and precision oncology. The Bild Laboratory investigates the molecular mechanisms that drive therapeutic response and resistance in cancer. Our multidisciplinary research integrates molecular biology, pharmacology, genomics, computational biology, and translational oncology to identify actionable signaling networks and develop predictive biomarkers that improve patient outcomes. The successful candidate will contribute to projects focused on understanding and targeting resistant cancer traits using advanced experimental and systems-level approaches.
Responsibilities
- Lead independent studies investigating the molecular, cellular, epigenetic, and signaling mechanisms underlying intrinsic and acquired treatment resistance in solid tumors.
- Design and perform molecular, cellular, and pharmacologic experiments using cell-based, ex vivo, and patient-derived cancer models.
- Characterize oncogenic pathways, adaptive cellular states, and resistance-associated vulnerabilities to identify promising therapeutic targets and combinations.
- Integrate molecular, genomic, transcriptomic, epigenetic, and phenotypic data to uncover actionable drivers of treatment response and resistance.
- Develop and validate predictive biomarkers of therapeutic outcomes, including blood-based genetic and epigenetic assays and methylation-based tests.
- Advance translational studies that support precision oncology clinical trials and biomarker-guided treatment strategies using City of Hope’s patient specimens, genomic technologies, single-cell platforms, computational resources, and clinical collaborations.
- Collaborate with basic, computational, and clinical investigators and present findings at laboratory meetings, institutional seminars, and scientific conferences.
- Prepare manuscripts for publication in high-impact journals and contribute to grant applications.
Requirements
- PhD, MD/PhD, PharmD, or equivalent doctoral degree in Cancer Biology, Pharmacology, Molecular Biology, Systems Biology, Bioengineering, Computational Biology, or a related discipline.
- Strong background in cancer biology and molecular signaling.
- Experience with one or more of the following:
- Cell culture and functional assays
- Molecular biology techniques
- CRISPR or genetic perturbation approaches
- Genomics, transcriptomics, or single-cell technologies
- Pharmacology and drug response studies
- Bioinformatics or computational analysis
- Excellent written and verbal communication skills.
- Demonstrated publication record in peer-reviewed journals.
Skills
- Experience studying therapeutic resistance in cancer.
- F
- .
Pay: "City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location." We'll put as
- but spec says use