Postdoctoral Associate - Drug metabolism and toxicity
About the role
The Center for Drug Discovery at Baylor College of Medicine in Houston, Texas, is seeking self-motivated candidates with a strong sense of teamwork, curiosity, and enthusiasm for biomedical research, specifically in drug metabolism and blood testis barrier. The lab is well-equipped with state-of-the-art equipment, including Thermos UHPLC-Q Exactive MS, Orbitrap Exploris 120, Thermo Quintus, and Imaging mass spectrometry.
Understanding drug metabolism can predict possible adverse events of drugs in clinic and reduce the risk of drug candidates in drug development. Determining chemical features that pass through the blood testis barrier will facilitate drug development for therapeutic targets behind the barrier. Strong scientific judgment, critical thinking, and the ability to identify important scientific questions are highly valued.
Responsibilities
- Plans, designs, and conducts animal experiments as well as cell cultures
- Characterizes drug metabolites using High-resolution LC-MS and NMR
- Analyzes LC-MS data from mouse tissue and plasma to evaluate their abilities for passing through BTB using imaging mass spectrometry
- Documents and interprets experimental results and reports to principal investigators
- Assists with manuscript preparation and writing
- Conducts literature searches and summarizes information in an appropriate format for a particular study
- Performs other job-related duties as assigned
Qualifications
The minimum qualification is an MD or Ph.D. in Basic Science, Health Science, or a related field, with no experience required.
Preferred qualifications include experience in LC-MS-based omics and imaging mass spectrometry method development and sample preparation, and data analysis, as well as strong academic integrity, independent research ability, and a collaborative team spirit.