POSTDOCTORAL ASSOCIATE - Droujinine Lab - Molecular & Cellular Biology

About Us

Scripps Research is a nonprofit biomedical institute ranked as one of the most influential in the world for its impact on innovation. We celebrated our 100-year legacy in 2024. This significant milestone marks a century of seminal discoveries in immunology, infectious diseases (such as COVID-19, flu, HIV), neuroscience, heart disease, cancer, and more. Located in La Jolla, California, the institute houses six research departments, multiple Nobel laureates, a top-ranked graduate school and a leading postdoctoral training program. Scripps Research encompasses two elite and highly innovative institutes, the Calibr-Skaggs Institute for Innovative Medicines and Scripps Research Translational Institute, which merge foundational studies in biology, chemistry and computer science with translational science to produce pioneering drugs and advances in digital and precision medicine. Together, we cultivate new scientific leaders and expand the frontiers of knowledge to deliver medical breakthroughs impacting human health around the globe.

Position Title

Postdoctoral Associate

Position Summary

We are seeking a highly motivated Postdoctoral Associate. Ideal candidate will lead their own project, and perform mammalian cell culture, in vivo mouse experiments, in vivo genetic screens, quantitative TMT mass spectrometry proteomics, metabolomics, western blot, pulldowns, DNA cloning, immunostaining, confocal microscopy, high throughput screens, and bioinformatic data analysis. Significant emphasis is placed on the professional development of the Postdoctoral Associate. More information on the project will be discussed during the interview process.

Lab Project Overview

To maintain homeostasis, organisms rely on internal signaling networks that orchestrate the physiological response across different tissues and organs. Intriguingly, perturbation in one tissue elicits secreted signals that transmit the information to other tissues and that these signals are important for maintenance of health and longevity. Secreted proteins are key components of interorgan signaling that coordinate organ functions by signaling over long distances. Destabilization of these interorgan signaling networks, responsible for the orchestration of physiological responses across organs, drives age-associated disease, including diabetes, cancer, or chronic inflammation. Despite this, the composition and activity of interorgan communication networks and their impact on aging and disease remain poorly defined. The Droujinine Lab has developed novel methods to identify and characterize novel secreted factors that coordinate organ functions in homeostasis and disease in mammalian systems. Specifically, we use proteomics and in vivo functional genomic screens to uncover the secreted proteins and cellular circuitry involved in homeostasis, obesity, and aging.

Contact

Contact: idroujinine@scripps.edu

Compensation

Postdoctoral Associates will be hired following the National Institute of Health and California’s exempt salary guidelines, which provide for a starting range of $70,304- $75,353. Consideration will be given to experience that exceeds the listed requirements.

Benefits

• Comprehensive Benefits Include Eligibility for retirement plans with employer contribution.
• Full suite of Health and Welfare plans including four medical plan options (including an HSA available option), dental, vision, life insurance, disability, EAP and more.
• Access to Dependent Flexible Spending Accounts.
• Paid Time Off - 5 days annually.
• Free, on-site Counseling Center which provides confidential counseling services to benefits-eligible employees.
• Free, on-site parking.
• Pet Insurance