Postdoctoral Associate - Deverman Lab

The Deverman lab at the Broad Institute of MIT & Harvard is looking for an exceptional and energetic postdoctoral researcher or research scientist to join a rapidly growing, multidisciplinary technology development research effort aimed at developing AAV vectors that enable targeted gene expression in a range of disease-relevant CNS neuronal populations. We seek a candidate to join an exciting and funded project aimed at developing gene regulatory elements and custom AAV capsids that will enable modern genetically encoded tools to be specifically expressed within specific neuronal subclasses. This project is a collaboration between multiple laboratories at the Broad Institute. The role will include project planning, hands-on bench work, reporting results to leadership, collaborators, funding agencies, and contributing to scientific manuscripts and presentations. The successful candidate will be an employee of the Broad Institute and will have access to a wide array of internal career development opportunities and scientific talks throughout the wider Harvard/MIT research ecosystem. CHARACTERISTIC DUTIES Develop, refine and apply novel high-throughput selection and screening methods to develop novel capsids and gene expression systemsApply gene delivery strategies to multiple in vivo and in vitro modelsUse standard molecular biology techniques for plasmid construction, PCR, qPCR, RNA and DNA extraction and detection, and next generation sequencing (NGS)Conduct and/or supervise the production, purification and evaluation of AAVTroubleshoot to resolve problems and participate in new technology evaluation, development and implementationDocument, compile, and analyze experimental dataAttend and present at team meetings to share results, plan projects and experimentsMake significant contributions to scientific manuscripts, funding agency reports, and conference presentationsSupervise the activities of one or more research associatesWork closely with team members to design, implement and troubleshoot experiments critical to the group’s collective success Qualifications 0-1+ years of related experienceA PhD in a relevant discipline molecular or cell biology, neuroscience, or related disciplinesExperience with molecular biology techniquesFamiliarity with NGS, high-throughput screening methods, immunohistochemistry/in situ hybridization, and production of gene delivery vectors is strongly desiredHands on experience with stereotaxic injectionsKnowledge of bioinformatics and statistics is helpful but not requiredOutstanding interpersonal and communication skillsDemonstrated track record of, and continued interest in, working as part of a large cross-disciplinary collaboration in a fast-paced research environmentExceptional organizational and time management skills Pay Range: $70,000.00/yr - $92,666.67/yr The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law. At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits. The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations. Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.