Postdoctoral Associate | Bennett Lab

About the role

The Bennett Lab at The Jackson Laboratory in Bar Harbor, ME, seeks a Postdoctoral Associate to contribute to the understanding of fundamental mechanisms governing the development of hematopoietic stem cells (HSCs) and their translation into regenerative medicine.

Responsibilities

• Plan, develop, execute, and analyze an independent research project focusing on TGF-β/BMP signaling regulation of pre-HSC maturation.
• Conduct mechanistic studies into the role of SMAD7 and related downstream effectors in HSC specification and maturation.
• Identify novel regulators of HSC emergence from hemogenic endothelium and map transcriptional states using single-cell and clonal barcoding approaches.
• Prepare manuscripts, fellowship applications, and conference presentations.
• Mentor junior lab members and contribute to a collaborative team environment.

Requirements

• Ph.D., M.D., or equivalent degree in biological sciences or related disciplines.
• Minimum of one first-author publication from graduate studies or prior postdoctoral work.
• Strong foundational training in molecular biology, cell biology, developmental biology, or stem cell biology.
• Excellent verbal and written communication skills.
• Self-motivated and capable of working independently and collaboratively.

Preferred Qualifications

• Experience or training in hematopoiesis, stem cell biology, developmental biology, or vascular biology.
• Mouse models, transplantation assays, or in vivo lineage tracing.
• Flow cytometry, cell sorting, and primary cell culture.
• Single-cell RNA-seq, ATAC-seq, spatial genomics, or related genomic technologies.
• Lentiviral systems or clonal barcoding.
• Computational biology, bioinformatics, or quantitative data analysis.

How to Apply

A complete application must include a cover letter describing past research accomplishments, current research interests, and career aspirations; a current CV; and the names and contact information of three references.

About JAX

The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.

EEO Statement

The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.