Post-Doctoral Scientist — Technical Services/Manufacturing Science (TS/MS)

Responsibilities

Post-Doctoral Scientists at Lilly are responsible for:

• Ensuring reliability of our manufacturing processes and systems
• Continuously searching for, developing and implementing improvements
• Driving technical projects in a rigorous manner for robust implementation
• Maintaining our processes in a state of compliance with US and global regulations
• Designing and developing drug processes and delivery systems

Requirements

• Ph.D. in scientific disciplines of Chemistry, Materials Chemistry, Chemical Biology or closely related field
• Qualified applicants must be authorized to work in the United States on a full-time basis

Key Objectives/Deliverables

• Understand the chemistry and stability (including oxidation/degradation pathways) of peptides and biomolecules
• Develop appropriate laboratory-scale models to assess manufacturing changes
• Understand the scientific principles required for bioproduct manufacturing of drug substances and drug products, including the interaction of molecule/solution chemistry with process equipment, drug product containers, and/or delivery systems
• Design, conduct, and analyze statistically designed experiments to deepen process understanding and optimize processing conditions
• Understand scale-up requirements and as needed, partner with the manufacturing sites to conduct appropriate scale-up work
• Provide technical support to process development areas as needed
• Document all work in an appropriate manner
• Mentor lab associates enhance their technical capabilities
• Participate in technology transfer as needed
• Travel 0 – 10%

Additional Skills/Preferences

• Desired Experience: Functional understanding of organic chemistry as applied to stability of peptides and biomolecules and characterization methods (preferred)
• Understanding of first principles that may impact absorption/desorption properties of various materials of construction
• Demonstrated record of scientific achievement
• Demonstrated problem solving abilities
• Ability to work well independently, as well as in teams
• Strong written and oral communication skills