Post Doctoral Research Fellow
University of Colorado · Aurora, CO · 1 wk ago
Analyst$63k–$77k/yrFull-time
Key Responsibilities
- Design and conduct preclinical radiopharmaceutical research studies across multiple stages of development.
- Perform radiolabeling procedures and quality control testing to ensure compound integrity and performance.
- Execute bioconjugation and in vitro characterization studies to evaluate radiopharmaceutical properties.
- Develop and maintain mammalian cell cultures and tumor models for experimental research.
- Conduct PET/SPECT imaging, biodistribution, dosimetry, and therapeutic efficacy studies.
- Analyze tissues and investigate biological mechanisms underlying treatment response.
- Contribute to translational molecular imaging, radiopharmaceutical development, and cancer therapy research, leveraging prior radiochemistry or radiopharmaceutical therapy experience to build an independent research program.
Professional Development Opportunities
- Training in translational radiopharmaceutical development, including study design, radiochemistry workflows, imaging and biodistribution studies, dosimetry, therapy response assessment, and regulatory-style documentation.
- Opportunities to contribute to the development of new research directions, including independent project ideas aligned with the candidate’s long-term career goals.
- Mentorship in manuscript preparation, grant writing, fellowship applications, and career development awards.
- Opportunities to mentor graduate students, technicians, summer students, and other trainees.
- Opportunities to collaborate with clinicians, radiochemists, imaging scientists, cancer biologists, medical physicists, and industry partners.
- Funding and support to attend and present at national scientific meetings.
Qualifications
- Minimum Qualifications: PhD, MD/PhD, PharmD/PhD, or equivalent doctoral degree in chemistry, radiochemistry, chemical biology, chemical engineering, biomedical engineering, pharmaceutical sciences, molecular imaging, cancer biology, molecular biology, or a related biomedical sciences field.
- Prior hands-on experience with radiochemistry, radiolabeling, radioactive material handling, radiopharmaceutical therapy, radiotracer development, or closely related radiopharmaceutical research.
- A strong interest in cancer imaging, targeted radionuclide therapy, radiopharmaceutical development, or translational oncology.
Preferred Qualifications
- Experience with alpha- or beta-particle radiopharmaceutical therapy.
- Experience with radiolabeled antibodies, antibody fragments, peptides, nanoparticles, small molecules, or pretargeted imaging/therapy systems.
- Experience with PET, SPECT, biodistribution studies, dosimetry, or quantitative imaging analysis.
- Experience with in vivo tumor models, including xenograft, orthotopic, metastatic, or patient-derived models.
- Experience with in vitro cancer biology assays, including 2D or 3D cell culture, organoids, viability assays, receptor binding/internalization assays, clonogenic survival, DNA damage assays, immunofluorescence, flow cytometry, Western blotting, or IHC.
- Experience with bioconjugation, antibody characterization, protein chemistry, size-exclusion chromatography, HPLC, stability testing, or related analytical methods.
- Experience analyzing and visualizing data using GraphPad Prism, ImageJ/FIJI, FlowJo, Python, R, CellProfiler, or related platforms.
- Experience preparing manuscripts, fellowship applications, grant applications, presentations, SOPs, IACUC protocols, radiation safety documentation, or regulatory-style reports.
- Evidence of scientific leadership, collaboration, mentorship, and ability to move projects from experimental planning through publication.