Post Doctoral Associate-B.I.O.N.I.C. Lab
University of Pittsburgh · Pittsburgh, PA · 3 wk ago
AnalystFull-time
Key Responsibilities
- Design and execute chronic in vivo ICMS and Wireless Axon photostimulation experiments in mouse visual cortex, combining two-photon calcium and hemodynamic imaging, intrinsic signal optical imaging, Neuropixels and high-density electrophysiology, and slice electrophysiology validation
- Contribute to NHP visual cortex ICMS experiments in the Gharbawie lab and to analysis of human somatosensory ICMS datasets in the Gaunt and Collinger groups, building the cross-species comparisons that the Inception framework requires
- Characterize boron-doped MCD and NCD diamond electrodes through electrochemistry (CV, EIS, voltage transients), photovoltaic and photothermal benchtop assays, and chronic in vivo biocompatibility, in coordination with the Li Lab (MSU) on device iteration
- Quantify how stimulation parameters (waveform, frequency, pulse width, irradiance) map onto cell-type-specific recruitment, mesoscale circuit dynamics, and behavioral or perceptual outcomes across species
- Build reproducible multimodal analysis pipelines in MATLAB, Python, and ImageJ or Fiji, with code released alongside publication
- Prepare first-author manuscripts, present at SfN, NER, and BRAIN PI meetings, and contribute to renewal and follow-on grant applications
- Mentor graduate and undergraduate trainees in surgical, imaging, electrochemical, and computational methods
Qualifications
- Ph.D. in Bioengineering, Neuroscience, Neurobiology, Biomedical Engineering, Electrical Engineering, Computer Science, Mechanical Engineering, Chemical Engineering, Physics, Optics, Materials Science, Molecular or Cellular Biology, Biochemistry, Chemistry, or Mathematics
- Proficiency in signal processing and quantitative analysis in MATLAB, Python, or equivalent, evidenced by first-author publication or shared code
- Strong scientific writing and oral communication, with manuscript and conference experience
- Ability to work independently and within an interdisciplinary team
Preferred (one Or More)
- In vivo multiphoton microscopy in visual or sensorimotor cortex, including stereotaxic surgery, chronic cranial window preparation, and AAV delivery
- ICMS, optogenetics, or neuromodulation experience, particularly in visual cortex
- NHP electrophysiology, NHP visual neuroscience, or analysis of human cortical recording datasets
- Electrochemistry (CV, EIS, voltage transient analysis), confocal microscopy, immunohistochemistry, or SEM characterization of neural electrodes
- Computational modeling of neural circuits, volume conduction, or stimulation-evoked activation
- Familiarity with brain-machine interface paradigms or sensory neuroprosthetic design