Physician Scientist, Cardiometabolic Genetics

Location: Tarrytown, NY or Cambridge, MA

About the Role

We are seeking a Physician Scientist to join our Cardiometabolic Therapeutic Area Genetics (TAG) team at the Regeneron Genetics Center (RGC). In this role, you will use massive-scale human exome sequencing to discover and validate new therapeutic targets in obesity and obesity-associated metabolic disease, accelerating therapeutic development through new human genetics and epidemiological insights. Collaborate with RGC teams and Regeneron's pre-clinical and clinical development teams to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

Responsibilities

• Generate key research questions, then design and execute studies and analyses to address them
• Interpret study results and summarize insights across formats — documents, presentations, patent applications, and publications — for different audiences
• Leverage RGC and Regeneron datasets, external resources, and the scientific/medical literature to address research questions, weighing quantitative and qualitative strength of evidence
• Support target nomination and validation by applying RGC's human genetics capabilities alongside Regeneron's therapeutics platforms and development modalities
• Partner with Clinical Development to evaluate clinical-stage programs and identify opportunities for human genetics studies that inform indication selection or safety evaluation
• Participate in the intellectual life of the Cardiometabolic TAG, RGC, and Regeneron at large, helping build an inclusive culture where everyone can perform at their best
• Represent the Therapeutic Area Genetics team in cross-functional initiatives across RGC and Regeneron

Requirements

• MD with a strong background in and knowledge of human genetics and genetic epidemiology; an MD/PhD with training in translational human genetics, genetic epidemiology, or a related discipline is preferred
• Proficiency with R or similar software, and familiarity with high-performance computing environments
• Experience integrating different data resources to translate initial genetic findings, and familiarity with meta-analysis of genome-wide summary statistics

Preferred Qualifications

• Experience as an investigator in Randomized Controlled Trials
• Experience in the clinical management or medical research of cardiometabolic disease

Benefits

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits.

Pay

Salary Range (annually): $176,100.00 - $287,300.00

Schedule

Many roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about on-site expectations for your role and location.