Physician Scientist, Cardiometabolic Genetics

Location: Tarrytown, NY or Cambridge, MA

About the role

We are seeking a Physician Scientist to join our Cardiometabolic Therapeutic Area Genetics (TAG) team at the Regeneron Genetics Center (RGC). In this role, you will use massive-scale human exome sequencing to discover and validate new therapeutic targets in obesity and obesity-associated metabolic disease, accelerating therapeutic development through new human genetics and epidemiological insights. You will collaborate with RGC teams and Regeneron's pre-clinical and clinical development teams, contributing to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

Responsibilities

• Generate key research questions, then design and execute studies and analyses to address them
• Interpret study results and summarize insights across formats such as documents, presentations, patent applications, and publications for different audiences
• Leverage RGC and Regeneron datasets, external resources, and the scientific/medical literature to address research questions, weighing quantitative and qualitative strength of evidence
• Support target nomination and validation by applying RGC's human genetics capabilities alongside Regeneron's therapeutics platforms and development modalities
• Partner with Clinical Development to evaluate clinical-stage programs and identify opportunities for human genetics studies that inform indication selection or safety evaluation
• Participate in the intellectual life of the Cardiometabolic TAG, RGC, and Regeneron at large, helping build an inclusive culture where everyone can perform at their best
• Represent the Therapeutic Area Genetics team in cross-functional initiatives across RGC and Regeneron

Requirements

• An MD with a strong background in and knowledge of human genetics and genetic epidemiology; an MD/PhD with training in translational human genetics, genetic epidemiology, or a related discipline is preferred
• Proficiency with R or similar software, and familiarity with high-performance computing environments
• Experience integrating different data resources to translate initial genetic findings, and familiarity with meta-analysis of genome-wide summary statistics

Preferred Qualifications

• Experience as an investigator in Randomized Controlled Trials
• Experience in the clinical management or medical research of cardiometabolic disease

Benefits

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role:

• Annual bonuses or other incentive plans
• Equity awards
• Pension or retirement benefits, 401(k) company match
• Health and wellness programs, fitness centers
• Insurance benefits (e.g., medical, dental, vision, life and disability)
• Paid time off
• Family support benefits

Pay

Salary Range (annually): $176,100.00 - $287,300.00