Organic and Conjugation Chemist

Responsibilities

• Perform multistep organic synthesis of linker-payload reagents under supervision
• Purify and characterize small molecules using techniques such as flash chromatography, HPLC, LC/MS, and NMR.
• Learn and perform bioconjugation of antibodies, peptides, and small molecule payloads and characterize conjugates using analytical techniques, such as HPLC, LC-MS, and SECD.
• Document experimental plans and procedures in electronic lab notebooks while following appropriate SOPs.
• Generate, analyze and summarize scientific data and provide regular updates on project results.
• Operate and maintain standard lab equipment.

Requirements

Win Heres What It Takes To Win We are all different, yet we all use our unique contributions to serve patients. The dedicated individual we seek is a scientist with these qualifications.

• Basic Qualifications: Master's Degree Or Bachelor's Degree and 2+ years of relevant experience OR Associates degree and 4 years of relevant experience OR High school diploma / GED and 6 years of relevant experience
• Preferred Qualifications: Experienced in organic synthesis including executing and optimizing chemical reactionsBasic understanding of purification and analytical methodsEagerness to learn chemical conjugation and characterization of ADCDemonstration of good lab practices, with particular attention to safetyStrong written and verbal communication skillsAbility to work comfortably within a dynamic team of scientists and engineers with diverse technical and cultural backgrounds

Qualifications

The qualified candidate will work at the interface of synthetic chemistry, biochemistry, and chemical biology, and apply their chemical synthesis skills in developing new antibody drug conjugates to support the advancement of drug discovery programs

Skills

As the Hybrid Modality Group at Amgen seeks a highly motivated scientist in the field of Antibody Drug Conjugates (ADC), the ideal candidate should possess:

• Experience in organic synthesis including executing and optimizing chemical reactions
• A basic understanding of purification and analytical methods
• Eagerness to learn chemical conjugation and characterization of ADC
• A demonstration of good lab practices, with particular attention to safety
• Strong written and verbal communication skills
• The ability to work comfortably within a dynamic team of scientists and engineers with diverse technical and cultural backgrounds

Benefits

What You Can Expect Of Us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

Pay

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

Schedule

In addition to the base salary, Amgen offers a total rewards plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include a comprehensive employee benefits package, including a retirement and savings plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

Work Location Type

Refer to the Work Location Type in the job posting to see if this applies.