NIH Postdoctoral Opportunity in Advancing PBPK Modeling of Fetoplacental Exposure

About the role

The postdoctoral research opportunity is available within the National Institutes of Health (NIH), specifically within the Office of Research Innovation, Validation, and Application (ORIVA). The goal is to generate quantitative data on placental transfer, permeability, and tissue-specific exposure to improve Physiologically Based Pharmacokinetic (PBPK) models.

Responsibilities

• Develop practical skills in advanced cell culture and human-relevant placenta-cardiomyocyte co-culture systems, including experimental design, compound exposure studies, and quantitative assessment of placental transfer and fetal tissue exposure.
• Under the guidance of a mentor, learn how the generated experimental data can be applied in PBPK model parameterization, model refinement, and validation.
• Enhance critical thinking, interdisciplinary collaboration, scientific communication, and data interpretation skills within the context of New Approach Methodologies (NAMs) for human-based risk assessment.

Requirements

• Must have a doctoral degree in a relevant field within the last 60 months or currently enrolled in a PhD program.
• Cell culture experience, preferably with placental or cardio physiology and/or modeling.
• U.S. citizenship, LPR status, or valid immigration status as per guidelines.

Qualifications

• Must be 18 years or older.
• Strong scientific capabilities and personal characteristics.
• Relevant experiences and publication list.

Skills

• Advanced cell culture techniques.
• Experimental design and data analysis.
• Interdisciplinary collaboration.
• Scientific communication.
• Data interpretation.
• New Approach Methodologies (NAMs).

Benefits

No specific benefits are mentioned in the job posting.

Pay

$88,000.00 yearly

Schedule

Fellows are expected to be fully engaged in-person at Research Triangle Park, NC.