NGS Senior Scientist 1

About the Role

We are seeking a Senior Scientist to lead the development and validation of new molecular assays and laboratory processes for deployment in our clinical laboratory.

Responsibilities

• Lead development of molecular assays and NGS workflows for high-throughput clinical laboratories.
• Design, execute, and analyze R&D studies with scientific rigor and attention to detail.
• Lead assay validation and clinical implementation from study design through launch, including workflow development, SOP creation, and documentation.
• Design and execute qualification and validation studies for reagents, instruments, equipment, and methods to support clinical deployment.
• Interpret data, troubleshoot issues, and drive process improvements.
• Collaborate across cross-functional teams and provide scientific leadership in a matrixed environment.
• Communicate clearly and effectively with technical and non-technical stakeholders.
• Train and mentor junior scientific staff and support implementation of new laboratory workflows.
• Support automation and technology initiatives to improve laboratory workflows.
• Manage multiple priorities and adapt quickly in a fast-paced environment.
• Travel up to 10% as needed.

Qualifications

• Ph.D. with 0 or more years of experience, or Master’s degree with 5+ years of relevant experience in molecular biology, assay development, or a related field.
• Experience in assay development and/or validation required.
• Experience in a clinical laboratory environment required; CAP/CLIA/NYSDOH experience preferred.
• Strong analytical, troubleshooting, and experimental design skills.
• Highly organized, detail-oriented, and committed to quality and accuracy.
• Proven ability to learn quickly and adapt to new processes, technologies, and workflows.
• Strong collaboration skills with the ability to lead across teams.
• Excellent oral and written communication skills.
• Ability to manage competing priorities and deadlines in a dynamic environment.

Preferred Technical Experience

• DNA/RNA extraction and purification methods.
• NGS library preparation, hybrid capture, and sequencing workflows.
• PCR-based techniques, including PCR, qPCR, RT-PCR, and ddPCR.
• Nucleic acid manipulation, quantitation, and analysis.
• Assay troubleshooting, root cause analysis, and workflow optimization.

Highly Desirable Experience

• Experience with FFPE tissue workflows.
• Experience with laboratory automation and liquid handling robotics.
• Experience developing and implementing protocols for CLIA-regulated laboratories.
• Familiarity with LIMS and laboratory data systems.

Pay

Pay Range: $95,000 - $120,000 USD. The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience.

Benefits

Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.