Senior Principal Scientist 1

About the role

The Senior Principal Scientist 1 at Halozyme is responsible for leading, designing, conducting, and analyzing experimental work to support Halozyme's drug delivery platform, alliance collaborations, and device research. This role involves identifying and developing technical innovations to promote future business growth and improvements that meet Halozyme's and its partners' requirements.

Responsibilities

• Plan, build, and conduct in vivo nonclinical exploratory and preclinical drug delivery studies to evaluate subcutaneous (SC) drug delivery and device technologies using Halozyme’s drug delivery platforms.
• Collaborate with platform teams to plan, build, conduct, analyze, and interpret data, and prepare nonclinical study reports and summaries to support drug delivery efforts.
• Ensure successful completion of nonclinical studies to meet clinical needs for Halozyme and its alliance partners.
• Support Halozyme’s and its partners' regulatory filings by drafting and/or reviewing clinical trial study protocols, drug administration instructions, pharmacy manuals, and other regulatory documents.
• Continue to develop experimental models to further expand drug delivery research and medical device development and knowledge.
• Provide preclinical research support to assess novel or alternative drug delivery technologies to grow Halozyme’s business portfolio.
• Enable innovation and technical strategy projects, generate IP, and contribute to scientific publications.
• Drive project timelines based on project needs and input from Innovation colleagues and cross-functional teams.
• Ensure compliance with company-established practices and procedures, including laboratory notebooks, computer files, quality and regulatory guidelines, and safety standards.
• Report and present scientific findings at appropriate scientific venues.
• Strive to be a Halozyme subject matter expert in one or more drug delivery fields.
• Provide leadership and set standards within the organization, driving toward a culture of quality, significant results, rapid delivery, collaboration, and Halozyme’s core values.

Requirements

• A Doctoral (Ph.D. or equivalent experience) in a suitable subject area like physiology, pharmacology, pharmaceutical sciences, or drug delivery is needed. This must be paired with at least 10 years of relevant industrial experience.
• An equivalent combination of experience and education may be considered.
• A strong background, in-depth knowledge, and hands-on technical ability in subcutaneous drug delivery.
• Proven problem-solving skills are a must.
• Expert knowledge of scientific principles and concepts.
• Demonstrated technical proficiency, scientific creativity, collaboration with others, and independent thought.
• A record of peer-reviewed publications involving preclinical models.
• Expertise in crafting and conducting nonclinical in vivo studies.
• Experience with medical devices, such as auto-injectors and on-body delivery systems.
• Experience with computer methods for data acquisition and analysis.
• Strong mathematical skills.
• Exercise judgment and build procedures and practices to determine appropriate action.
• Ability to communicate clearly and professionally both verbally and in written format.
• Demonstrated leadership capabilities to develop a high-performing team, inspire change and influence internal and external collaborators.
• Self-motivated, well-organized, with the ability to work independently and enjoy scientific investigation and thinking, proactively identifying issues, and developing solutions in a collaborative multidisciplinary environment.

Qualifications

• Doctoral (Ph.D. or equivalent experience) in a suitable subject area like physiology, pharmacology, pharmaceutical sciences, or drug delivery.
• At least 10 years of relevant industrial experience.
• Equivalent combination of experience and education may be considered.
• Master's (M.S. or equivalent experience) and 15 years of experience, or a Bachelor's (BS or equivalent experience) plus 20 years of experience.

Skills

• Subcutaneous drug delivery expertise.
• Problem-solving skills.
• Scientific creativity.
• Collaboration with others.
• Independent thought.
• Peer-reviewed publications.
• Data analysis and modeling.
• Regulatory document preparation.
• Medical device knowledge.
• Computer methods for data acquisition.
• Mathematical skills.
• Communication skills.
• Leadership capabilities.

Benefits

• Full and comprehensive benefits program, including an Employee Stock Purchase Program and 401(k) matching.
• Opportunities to advance in an environment that values learning, growth, and career progression through internal programs and tuition reimbursement.
• A collaborative, innovative team that works as one to amplify your impact—on your career, the work you do, and patients’ lives.

Pay

The most likely base pay range for this position is $180,000 - $240,000 per year. Several factors, such as experience, tenure, skills, and particular business needs, will determine an individual’s exact level of compensation. Base salary is only one element of employee compensation at Halozyme. Total compensation could include bonuses, sales incentives, and equity awards.

Schedule

The most likely schedule for this position is full-time, with occasional travel up to 20% of the time.