Jobs · Research · Indiana

Natural Products Chemist

Corteva Agriscience · Indianapolis, IN · 1 mo ago
ResearchFull-time

About the role

The Molecular Platforms team in Corteva Agriscience plays a critical role in the discovery, development, and optimization of microbial and small molecule natural product active ingredients. We are seeking a Natural Products Chemist to join our multi-disciplinary team at Indianapolis Global Headquarters as we grow our pipeline of sustainable products.

What You'll Do

  • Develop and execute isolation methods for natural products and metabolites from complex matrices (e.g., environmental, microbial, or plant) via chromatographic and other techniques.
  • Elucidate the structure of complex natural products using a variety of spectroscopic and analytical techniques.
  • Develop and optimize methods for the extraction, detection, and quantitation of secondary metabolites from microbial fermentation samples.
  • Promote information sharing and collaborate with scientists across disciplines (e.g., synthetic chemists, biologists, data scientists, metabolomics scientists) in a team-oriented environment.

What Skills You Need

  • Ph.D. in natural products/organic chemistry or a related field.
  • Isolation of secondary metabolites or similar natural products from complex biochemical matrices.
  • Broad range of separation techniques, including analytical and preparative scale chromatography (e.g. RP-HPLC, NP-HPLC, HILIC, Ion exchange, SEC, SPE, SFC).
  • Structure elucidation of complex secondary metabolites using both 1D, 2D NMR techniques and mass spectrometry.
  • Ability to design experiments and critically interpret results.
  • Excellent communication, collaboration, and presentation skills.
  • Meticulous organization and attention to detail.
  • A strong desire to make an impact on global food security.

Preferred Skills

  • A background in natural products chemistry and knowledge of natural product biosynthetic pathways.
  • Demonstrated success in isolation of many natural products in a collaborative environment.
  • Experience with the isolation and characterization of microbial natural products.
  • Experience in using density functional theory (DFT) methods for structure elucidation of natural products.
  • Experience or familiarity with microbiology and fermentation techniques to enable natural product isolation.
  • Familiarity with automation (e.g., liquid handing).

Benefits

  • Numerous development opportunities offered to build your skills
  • Be part of a company with a higher purpose and contribute to making the world a better place
  • Health benefits for you and your family on your first day of employment
  • Four weeks of paid time off and two weeks of well-being pay per year, plus paid holidays
  • Excellent parental leave which includes a minimum of 16 weeks for mother and father
  • Future planning with our competitive retirement savings plan and tuition reimbursement program

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