National Director – Field Medical Affairs - Geography - United States

About the Company

At Edgewise Therapeutics, we are focused on advancing novel, muscle-targeted therapeutics for serious cardiovascular and cardiometabolic conditions with significant unmet need. Leveraging our expertise in muscle biology and small molecule drug development, we are building a cardiovascular pipeline that includes programs for hypertrophic cardiomyopathy, heart failure, and other serious cardiovascular diseases. We’re building a passionate, experienced team committed to tackling complex scientific and clinical challenges and delivering meaningful outcomes for patients.

About the Role

Edgewise is seeking a strategic and execution-driven Field Medical Affairs Lead to build, lead, and spearhead our US Field Medical organization for clinical development advancement and medical launch readiness. This field-based, non-promotional medical and scientific leadership role is responsible for leading a National Field Medical team comprised of Medical Science Liaisons (MSLs). The National Director will develop the Field Medical strategy for their team, ensuring alignment with the Company’s overarching Medical and Field Medical strategy, and focus on delivering impact and improving patient care.

Responsibilities

• In partnership with Clinical and Medical leadership, develop a Field Medical strategy plan as part of clinical development advancement and launch readiness across the Company’s cardiovascular programs.
• Define external stakeholder mapping and engagement strategy incorporating cross-functional partnership with relevant internal stakeholders.
• Develop and translate medical strategies and actionable customer insights into field medical initiatives, ensuring successful execution by working with cross-functional stakeholders.
• In collaboration with the Head of Field Medical Affairs, define Field Medical impact and analytics needed to ensure maximal performance and impact of the field medical team to achieve desired business outcomes.
• Provide scientific support for advisory boards, including preparation, facilitation, and follow-up.
• Attend scientific congresses and symposia to gather and disseminate relevant scientific information. Staff medical booth, as needed.
• Collaborate cross-functionally with internal stakeholders (e.g., Clinical Development, Regulatory, Commercial, and Pharmacovigilance) to ensure scientific alignment.
• Disseminate medical insights and competitive intelligence to inform company strategy and development programs.

Requirements

• Accredited doctorate degree in a life-science or basic-science discipline (Pharm.D., D.Sc., D.N.P., Ph.D., or M.D./D.O.) strongly preferred.
• Minimum of 10+ years' experience as an MSL or in a field medical/scientific role within the pharmaceutical or biotech industry.
• Minimum of 2+ years of experience leading and building teams.
• A demonstrated ability to effectively lead, direct, coach, manage issues, and resolve conflicts for scientific and medical colleagues at all skill and knowledge levels is essential. Previous Field Medical leadership experience is preferred.
• Ability to build, scale, and lead high-performing field organizations, including talent strategy, succession planning, and development of managers.
• Prior experience in cardiology or rare diseases, preferably related to HCM and heart failure.
• Strong strategic thinking with ability to translate external insights and scientific data into integrated medical strategies and clear execution priorities.
• Excellent communication, influence, and presentation skills; ability to represent Field Medical Affairs credibly with senior internal stakeholders and external experts.
• Proven success managing both internal and external stakeholders in a dynamic, matrixed organization.
• Recognized as a valued collaborator and contributor within cross-functional teams.
• Deep scientific knowledge and passion for cardiovascular medicine.
• Ability to travel up to 60–70% overnight stays, as needed. May include international travel.
• Self-starter with strong organizational skills and the ability to work independently in a fast-paced, entrepreneurial environment.
• Demonstrated ability to efficiently manage time and priorities, lead projects while valuing input from others, and operate with a high level of integrity, professionalism, and initiative.

Pay

Salary range: $230,000 - $260,000, title and salary commensurate with experience.

Benefits

• Health benefits
• Discretionary bonus plan
• Stock option grants
• Stock purchase plan
• 401(k) with match
• Paid time off