National Account Director (Government Payers)

About the role

Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a commercial-stage biopharmaceutical company developing medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference (RNAi) mechanism to induce rapid, deep, and durable knockdown of target genes.

The National Account Director (NAD) will play a critical role in enabling patient access to Arrowhead’s first commercial asset—Redemplo (plozasiran, siRNA targeting APOC3)—as well as an expanding pipeline of innovative therapies. Redemplo has demonstrated compelling clinical data and received approval in November 2025 for the treatment of Familial Chylomicronemia Syndrome (FCS), with late-stage development continuing for Severe Hypertriglyceridemia (SHTG).

This field-based role requires periodic travel to Arrowhead's corporate headquarters in Pasadena, CA, as business needs dictate.

Responsibilities

• Strengthen relationships with key government accounts, including Managed Medicaid, Fee-for-Service Medicaid, the Department of Veterans Affairs, DoD/TRICARE, Indian Health Service, and Humana Medicare.
• Communicate product clinical and economic value to payers and key decision-makers.
• Create and maintain comprehensive account plans supporting launch and post-launch strategies.
• Lead contract negotiations, evaluate performance metrics, and ensure organizational alignment.
• Help develop the organizational structure and capabilities required to support effective payer engagement across the expanding U.S. Arrowhead portfolio.
• Monitor sales implications for each payer negotiation and take action to establish optimal access.
• Collaborate with cross-functional teams, including Sales, Medical Affairs, Commercial Analytics, Finance, and Compliance, to address access challenges.
• Provide market intelligence updates on payer trends, coverage determinations, and healthcare policy changes.
• Present payer policy insights at internal business reviews, national conferences, and sales meetings to align strategic priorities.
• Ensure full compliance with U.S. healthcare regulations, legal standards, and corporate policies.

Requirements

• Bachelor’s degree.
• 12+ years of pharmaceutical/biotech experience with a strong background in field-based market access, payer engagement, or managed markets.
• 5+ years of previous national account payer experience with established, deep-rooted relationships across government payer channels, including Managed Medicaid (MCOs), Fee-for-Service Medicaid, the Department of Veterans Affairs, DoD/TRICARE, Indian Health Service, and Humana Medicare.
• Strong understanding of commercial and Medicare Part D managed care processes.
• Previous experience launching rare disease/cardiometabolic medicines highly desired.
• Experience managing national and local contracting initiatives in managed care organizations.
• Demonstrated ability to drive results and influence cross-functionally without direct authority to support an expanding portfolio of innovative therapies.
• Excellent communication, negotiation, and presentation skills.
• Ability to translate complex scientific and economic data into payer-relevant insights.
• Self-motivated, collaborative, and able to operate with strategic independence.
• Willingness to travel up to 50%.

Preferred Qualifications

• Advanced degree (MBA, MPH, PharmD).

Pay

California pay range: $230,000 USD - $250,000 USD.

Benefits

Arrowhead provides competitive salaries and an excellent benefit package.