mRNA Process Development Senior Scientist

At Eurofins Professional Scientific Services (PSS), we focus on your professional growth, providing opportunities to break into the biopharmaceutical industry and develop your career from the ground up. With supportive teams and tools, we invest in our employees while promoting work-life balance and offering a competitive benefits package. Eurofins Scientific is an international life sciences company delivering analytical testing services to ensure safety, health, and sustainability across food, water, medicines, and more. As a global leader in testing and laboratory services, Eurofins supports industries with genomics, discovery pharmacology, forensics, and clinical studies.

About the role

We are seeking a Process Development Scientist to join our messenger-RNA (mRNA) process development team. The successful candidate will contribute to process characterization and tech transfer of programs in clinical development, with knowledge of GMP regulatory expectations for biologic gene-edited material. Direct experience developing, characterizing, scaling, or supporting GMP processes for mRNA is strongly preferred.

Responsibilities

• Design, execute, and analyze experiments to develop and optimize mRNA process characterization techniques.
• Evaluate process performance and identify opportunities for productivity improvements.
• Support the transition of development-stage processes toward GMP-compliant manufacturing by establishing scalable, robust, and well-characterized process parameters.
• Develop scalable processes for plasmid DNA production using fermentation systems.
• Operate and troubleshoot bioreactors/fermenters.
• Develop, execute, optimize, and troubleshoot in vitro transcription (IVT) process development activities.
• Develop, execute, optimize, and troubleshoot chromatography systems including Cytiva AKTA Avant for purification process development and scale-up studies.
• Develop, execute, optimize, and troubleshoot chromatography systems including Agilent 1260 HPLC/UHPLC systems for nucleic acid analysis, impurity profiling, quantitation, and process characterization.
• Analyze and interpret data to support process optimization, troubleshooting, and technology transfer activities.
• Author and review GMP-relevant technical reports, protocols, batch records, and development summaries.
• Present findings to management and project teams.
• Uphold lab safety to the highest level of standards.

Qualifications

• B.S. degree in chemistry, chemical engineering, or biochemistry (or related field) with 4+ years of relevant laboratory experience.
• M.S. degree in chemistry, chemical engineering, or biochemistry (or related field) with 2+ years of relevant laboratory experience.
• Ph.D. in chemistry, chemical engineering, or biochemistry (or related field) with at least 6 months of relevant laboratory experience.
• Experience supporting the process development and manufacturing of protein, AAV, or mRNA therapeutics (experience with mRNA process development is preferred).
• Experience with process characterization and validation studies.
• Working knowledge of cGMP regulations and technology transfer activities.
• Experience with IVT processes and operating bioreactors/fermenters.
• Experience with downstream purification and analytical processes: TFF and chromatography including Akta Avant and Agilent 1260 systems (experience with ELISA is a plus).
• Excellent communication, technical writing, and presentation skills.
• Strong attention to detail, organizational, work planning, problem solving, and critical thinking skills.
• Ability to work independently and autonomously with little supervision.
• Authorization to work in the United States indefinitely without restriction or sponsorship.

Schedule

Full Time, Monday-Friday, 8am-5pm. Candidates currently living within a commutable distance of Boston, MA are encouraged to apply.

Benefits

• Comprehensive medical coverage, dental, and vision options.
• Life and disability insurance.
• 401(k) with company match.
• Paid vacation and holidays.
• Eligibility for yearly goal-based bonus & merit-based increases.

Pay

$40.00-$46.00 per hour based on education and related experience.