Member of the Technical Staff, Biological Data
Output Biosciences · Buffalo-Niagara Falls Area · 1 wk ago
EngineeringFull-time
About the role
The Role Output is developing a biological reasoning model that learns at the scale and complexity of life, enabling novel drug treatments. This role requires expertise in molecular biology and computational methods.
Responsibilities
- Develop and expand training datasets for biological models, incorporating molecular principles and diverse data sources.
- Design and implement benchmarks to evaluate model performance against real-world molecular phenomena.
- Collaborate with model researchers to determine optimal training data strategies and integration methods across various biological scales and modalities.
- Create rigorous data splitting and evaluation protocols to ensure model generalization and robustness.
- Stay updated with the latest biological data sources, experimental methods, and molecular databases, identifying new training signals.
Requirements
- PhD in computational biology, biophysics, structural biology, chemistry, biochemistry, or a related biological field with 2+ years of post-doctoral or industry research experience.
- Deep understanding of molecular interactions, protein structure, and biological data at the molecular level.
- Experience working with large-scale biological or molecular datasets, including sourcing, cleaning, integrating, and analyzing heterogeneous data.
- Strong programming skills in Python, capable of building computational pipelines for data processing at scale.
- Understanding of what machine learning models require from training data, including coverage, quality, balance, and evaluation rigor.
- Experience with computational biology tools such as structure prediction, molecular docking, or virtual screening.
- Experience training or evaluating machine learning models, particularly on molecular or biological data.
- Publications in computational biology, bioinformatics, or molecular informatics.
- A background in cheminformatics or molecular data analysis.
- Experience working with protein or molecular language models.
Qualifications
- Passionate about computational biology and its potential to solve complex biological problems.
- Ability to think critically about data construction and its implications for model performance.
- Strong communication and collaboration skills, able to work effectively with model researchers and other interdisciplinary teams.
- Commitment to excellence and continuous improvement in the field of computational biology.
Skills
- Python programming
- Data processing and analysis
- Benchmarking and model evaluation
- Data integration and heterogeneity handling
- Machine learning model development and optimization
- Biological data interpretation and analysis
Benefits
Our values include heart, excellence, practicality, honesty, and fun. We offer a competitive salary and equity, excellent medical, dental, and vision coverage, and a supportive, collaborative work environment.
Pay
Competitive salary and equity in a growing, well-funded startup.
Schedule
Flexible schedule to accommodate the needs of the role and the individual.
Our Values
- Heart: We foster a culture of ownership and passion.
- Excellence: We have an unwavering commitment to excellence and continuous improvement.
- Practicality: We value practicality and results-oriented thinking.
- Honesty: We place a high value on honesty and directness.
- Fun: We believe that life is too short to not have fun. Our goal is to create a workplace that is fun, engaging, rewarding, and fulfilling.
What We Offer
- Healthy feedback-focused environment to help you strive and grow.
- Competitive salary and equity in a growing, well-funded startup.
- Excellent medical, dental, and vision coverage.