Medical Director

Compass Therapeutics, Inc. is an oncology-focused biopharmaceutical company discovering and developing proprietary antibody-based therapeutics. Our robust pipeline includes four clinical assets spanning all phases of studies, with novel mechanisms of action and first-in-class or best-in-class potential across multiple tumor types. Our lead clinical-stage asset, tovecimig, has completed a randomized, late-stage biliary tract cancer study, and we are preparing for a BLA submission. This is a pivotal moment to join us and help make a meaningful impact on patients’ lives.

About the role

The Medical Director will report directly to the Chief Medical Officer and lead key medical and clinical initiatives while collaborating across the organization. This position is on-site at our Brighton, MA office with an expectation of 4 days per week in the office.

Responsibilities

• Ensure Compass corporate and Medical goals are on track to reach milestones within established timelines, while delivering within applicable quality and regulatory standards.
• Execute successful clinical research activities according to the strategic plan to support product approval, including management of internal and external stakeholders and partners.
• Lead relationships with Clinical Research Organizations (CROs) and other key clinical vendors, ensuring quality, patient safety, and compliance with GCP standards.
• Monitor oncology-based clinical trials to achieve milestones, identify and mitigate risks, and adjust study protocols as needed.
• Oversee data management, safety, database review, medical cleaning, regulatory compliance, and related activities.
• Partner with Clinical Operations on study start-up and site initiation, including site initiation visits (SIVs).
• Collaborate cross-functionally with the Executive Leadership Team, Clinical leadership, and key colleagues in the execution of clinical research activities.
• Develop and maintain strong external relationships, especially with KOLs and Study Investigators.
• Evaluate clinical trial data to determine potential efficacy, safety profile, and other key clinical indicators.
• Utilize scientific and medical expertise to resolve study-related issues as they arise.
• Maintain a high level of clinical and scientific expertise in oncology through literature review, scientific conferences, and relationships with KOLs and investigators.
• Maintain ethical standards of the highest level and comply with all relevant ethical, regulatory, and legal standards.

Requirements

• MD with experience in oncology, immune-oncology, or a relevant medical specialty area.
• 5+ years of life sciences industry experience, with strong oncology medical oversight experience.
• Clinical drug development industry experience, with significant knowledge and experience in the execution of clinical trials.
• Deep knowledge and expertise in Oncology, and understanding of cross-functional teams.
• Thorough understanding of applicable regulatory agency guidelines to ensure appropriate conduct of clinical studies.
• Exemplary written and verbal business communication skills, including executive presence.
• Advanced working knowledge of FDA and all required regulatory guidelines.
• Self-motivated, analytical, meticulous, flexible, and eager to take on new tasks.
• Ability to collaborate in a fast-paced, team-oriented environment; desire to mentor junior leaders is preferred.
• Proficiency in utilizing Microsoft Office Suite and other relevant tools.

Pay

Base Salary Range: $250,000 USD - $400,000 USD

Benefits

• Comprehensive and market-leading compensation package, including base salary, discretionary bonus, and meaningful equity participation.
• Subsidized medical, dental, and vision premiums.
• Health reimbursement arrangement and flexible spending accounts.
• Gym membership and employee assistance program.
• Life insurance.
• 401(k) and Roth 401(k) programs with a 6% company match.
• Company parking and commuter reimbursement.
• Substantial vacation and leave policies, including summer Fridays and a winter shutdown week.
• Company-wide training, tuition and training reimbursement, recognition awards, and comprehensive performance management.
• Compass Culture Committee initiatives, including events, charitable causes, and programs aligned with company values.