Mass Spectrometry Scientist

Parallel Squared Technology Institute (PTI) is a non-profit research institute aiming to catalyze a leap in protein analysis technology and use it to explore new biological frontiers. PTI supports open research and educational opportunities supporting rapid career development for scientists, engineers, and mathematicians. We develop mass tags enabling a new framework for multiplexed protein analysis by mass spectrometry towards achieving a 100-fold increase in throughput. Scientists at and collaborating with the institute will use these gains to directly investigate disease mechanisms, with Alzheimer's disease and aging among the first focuses.

About the role

We are looking for an experienced Mass Spectrometry Scientist who will maintain MS instruments for running multitudes of samples across various projects, advance and execute hypothesis-driven experiments, and contribute to a diverse team of chemists, machine learning engineers, biologists, and mass spectrometrists. Members of PTI will be supported with industry-level resources to lead research projects and disseminate discoveries through publications, presentations, and public data portals.

Responsibilities

• Set up, operate, and maintain (e.g., vent and clean) mass spectrometers from multiple major vendors (Thermo, Bruker, Sciex, etc.).
• Analyze experimental data and interpret results for internal and public presentation.
• Train team members to use instruments independently.
• Design relevant proteomic experiments.
• Perform protein sample preparation.
• Prepare lab reagents and media.
• Manage inventory, prepare reagents and samples.
• Communicate with purchasing and negotiate with vendors.
• Manage MTAs, software licenses, service contracts, and other documentation.

Requirements

• Master’s or PhD in Biology, Biochemistry, or Chemistry.
• 5+ years of experience maintaining mass spectrometers.
• Demonstrated experience optimizing LC-MS/MS methods for bottom-up proteomics (e.g., DDA/DIA/prioritized approaches).
• Demonstrated mastery of chemistry techniques or molecular & cellular biology techniques.
• Enthusiasm and interest in bioanalytical chemistry.
• High level of initiative, flexibility, excellent communication, and teamwork skills.
• Attention to detail and strong time management skills.

Preferred Qualifications

• Experience with mass spectrometry technological development (hardware or software).
• Proficiency with statistical and computational methods (e.g., coding in Python/R).

Benefits

• Excellent medical, dental, and vision insurance with $0 premium options for you and your family (20+ plan options available).
• Company-paid group life, AD&D, long- and short-term disability insurance.
• 15 days PTO + 10 sick days per year.
• 18 company holidays + your birthday off.
• $5,000 per year educational reimbursement.
• Up to 16 weeks paid parental leave.

Pay

$86,000 - $119,000 a year