Manufacturing Associate II, Cell Culture (Days)

Our factories run 24/7 operations. Manufacturing teams work 12-hour shifts (either Days or Nights) on a 2-2-3 calendar rotation. This role follows a 2-2-3 calendar rotation on days (6:00 AM – 6:00 PM ET).

About the role

Manufacturing Associates perform processing steps and manufacturing support activities in our Drug Substance facility in Research Triangle Park (RTP). These teams are the backbone of our operations, playing a critical role in delivering therapies to patients. Teams are organized by biomanufacturing process steps, including Upstream (Cell Culture), Downstream (Purification), and Media & Solution Preparation. This role focuses on Upstream Cell Culture operations in a clean environment governed by Current Good Manufacturing Practices (cGMP).

Responsibilities

• Prepare bioreactors by executing automated CIP/SIP recipes using DeltaV
• Perform filtration, centrifugation, and harvest operations
• Standardize and calibrate pH and DO probes during bioreactor preparation
• Perform inoculation of bioreactors across multiple scales
• Support cell growth operations, including media feeds and process additions
• Conduct routine sampling and in-process testing to monitor product quality
• Standardize and maintain laboratory and manufacturing equipment, including:
  • Vi-Cell Blu/XR
  • Osmometer
  • pH meters
  • RapidPoint BGA
  • Conductivity meters
  • Biosafety cabinets
  • Small-scale centrifuges
• Accurately document activities in accordance with cGMP and SOP requirements
• Maintain a clean, safe, and compliant manufacturing environment
• Collaborate cross-functionally with Manufacturing, MSAT, Quality, and Engineering teams

Requirements

• Bachelor’s degree from an accredited college or university (STEM preferred) and 0+ years of direct experience, or
• BioWorks Certificate or associate's degree (STEM preferred) and 0+ years of direct experience, or
• High School Diploma (or equivalent) and a minimum of 0.5 years of direct experience
• Previous experience in a GxP environment
• Ability to follow SOPs and work effectively on shift schedules
• Demonstrated documentation and data integrity skills
• Understanding of aseptic technique and cleanroom practices (preferred)

Pay

The base compensation range for this role is $23.56 - $30.77 per hour. Base salary offered is determined through an analytical approach utilizing factors including, but not limited to, relevant skills and experience, job location, and internal equity.

Benefits

• Medical, Dental, Vision, and Life insurance
• Fitness and Wellness programs, including a fitness reimbursement
• Short- and Long-Term Disability insurance
• A minimum of 15 days of paid vacation and an additional end-of-year shutdown (Dec 26-Dec 31)
• Up to 12 company-paid holidays + 3 paid days off for Personal Significance
• 80 hours of sick time per calendar year
• Paid Maternity and Parental Leave
• 401(k) program participation with company-matched contributions
• Employee stock purchase plan
• Tuition reimbursement of up to $10,000 per calendar year
• Employee Resource Groups participation
• Short-term and long-term incentives, including cash bonus and equity opportunities

About the company

We are a global team with a commitment to excellence and a pioneering spirit. As a mid-sized biotechnology company, we provide stability and resources while fostering an environment where individual contributions make a significant impact. Our team delivers life-changing medicines, with every role playing a vital part in our mission.