Lead Statistician HEOR

Essential Duties and Responsibilities

• Draft SAPs for projects that require use of advanced statistical methodologies
• Advises junior and mid-level staff on methodology and approach on projects requiring use of standard statistical methodologies
• Reviews and approves SAPs projects that require use of standard statistical methodologies
• Lead implementation & interpretation of analyses on projects requiring the use of advanced statistical methodologies
• Provides guidance and advice as needed for junior and mid-level staff on projects requiring use of standard statistical methodologies
• Lead proposal development in familiar project-types or take a supportive role for more complex projects
• Determine technical approach, review proposal drafts and take responsibility of stats components
• Get involved in client discussions
• Obtain significant levels of repeat business from clients
• Lead technical response to requests for proposals, generate repeat work and amendments
• Identify opportunities for new work
• Advise and peer-review budget
• Communicate effectively and proactively with project teams
• Able to work with and delegate to junior and mid-level staff, responsible for deliverable quality and integrity
• Review and support presentations by more junior staff
• Provide on-the-spot problem-solving and consulting in discussions of results
• Contribute to the conceptualization and development of novel/bespoke solutions to meet client project needs
• Independently investigate the properties, applicability and advantages/disadvantages of both: Methodologies developed by Evidera as bespoke solutions to client projects Newly published methodologies, and seeks senior input when needed
• Lead the development of parts of tools/macros that improve efficiency of project execution, seeking senior input when needed
• Provide technical training on the tools developed within HEMA Scientific
• Develop and implement the best scientific practices/guidelines, product development/new methods, or deliverable standards
• Support external thought leadership through publications and workshops
• Look for opportunities to disseminate knowledge

Financial and managerial

• Responsible for achieving utilization and proposal and sales targets
• Supervise and mentor junior and mid-level staff, involvement in hiring and development of staff, conducting performance reviews

Education, Professional Skills & Experience

• PhD in Biostatistics/Statistics or related field with 4+ years of experience
• MSc in Biostatistics/Statistics or related field with 6+ years of experience
• BSc in Biostatistics/Statistics or related field with 8+ years of experience
• Strong basis in fundamental statistical concepts and methods, and expertise with techniques such as regression analysis (continuous, binary, count data), longitudinal data analysis (mixed effects linear regression), parametric and semi-parametric survival analysis, meta-analysis, indirect treatment comparisons, issues related to missing data, etc.
• Practical experience in standard statistical applications in health economics such as: Standard parametric and semi-parametric survival analyses Flexible parametric models (spline, piecewise) ITC methods (Bucher, network meta-analyses [NMA], matching-adjusted indirect comparisons [MAICs], simulated treatment comparisons) Country-specific utility analyses to inform CEMs
• Familiarity with complex methods, including: Projecting incomplete survival data using Bayesian parametric survival models with informative priors Adjustment for treatment switching (rank preserving structural failure time, inverse probability of censoring weighting, two-stage estimation) Mixture cure models multi-state models Multilevel network meta-regression and fractional polynomial NMA Surrogacy analyses
• Statistical programming skills with standard software, including R and/or STATA/SAS
• Ability to communicate analysis plans and results to clients or colleagues who may have limited background in statistics
• Scientific visibility in terms of authorship of peer-reviewed publications, podium presentations and posters at conferences
• Leading development and deployment of technology solutions for initiatives involving automation or AI-enablement in statistics and other areas in health economics and market access will be an asset