Lead Scientist

Location: Durham, North Carolina (Hybrid)

About the role

Genomics is a science-led transatlantic TechBio combining large-scale genetic and health data with proprietary analytics to accelerate drug discovery and advance predictive, preventative healthcare. We are united by a single vision to help people live longer healthier lives, using the power of genomics.

Genomics aims to help people live longer, healthier lives in two ways: super-charging drug discovery and development for novel treatments with our AI-enabled advanced genetic analytics platform, and by helping people understand their personal risk of common chronic diseases through polygenic risk scores - giving doctors and health systems the chance to get the right people into the right prevention, screening and treatment programmes at the right time.

A typical week might see you framing the right scientific question for a complex genomic analysis, then structuring the work so your team can run with it. You make the decisive calls when a problem is ambiguous or novel, and you roll up your sleeves on the toughest analyses yourself rather than watching from the sidelines. You might act as strategic consultant to an external pharma or biotech partner in the morning - fielding sharp technical questions in real time - and mentor a junior colleague through a tricky method in the afternoon. Throughout, you are translating dense genomic results into clear, actionable insight, spotting delivery risks before they become problems, and keeping one eye on scientific quality and the other on scope, timelines and the partner experience.

Responsibilities

• Frame scientific questions for complex genomic analyses and structure work for team execution.
• Make decisive calls on ambiguous or novel problems, performing hands-on analysis when needed.
• Act as a strategic consultant to external pharma or biotech partners, addressing technical questions in real time.
• Mentor junior colleagues through challenging methodologies.
• Translate dense genomic results into clear, actionable insights for stakeholders.
• Identify and mitigate delivery risks while balancing scientific quality, scope, timelines, and partner experience.

Requirements

• PhD (or equivalent experience) in a quantitative life-science discipline: genomics, bioinformatics, computational biology, statistics, or a closely related field.
• Experience leading complex scientific projects end-to-end, managing timelines, scope, and stakeholder expectations.
• Fluency in genomic data analysis at scale, including large genetic datasets, GWAS, polygenic risk scores, and related methodologies.
• Robust grasp of statistical human genetics, applied inventively in a partner-facing environment.
• Ability to unravel complex genomic data and translate findings into actionable consulting insights.
• Strong communication skills for both technical and non-technical audiences.
• Sound analytical judgement under uncertainty and ability to collaborate across teams.
• Commitment to mentoring and developing others.

Benefits

• Competitive Salary: Externally benchmarked annually to ensure top-of-market compensation.
• Career Growth: Clear, open progression framework with defined paths to promotion.
• Continuous Learning: Access to external courses and a wide library of learning and development materials.
• Holiday: 25 days annual leave, plus bank holidays, plus an extra 3-day company-wide shutdown at year-end.
• Financial & Health Security: Market-leading pension scheme, comprehensive private health insurance for you and your family (no excess), critical illness, and life assurance.
• Enhanced Leave: Enhanced paid family leave for all new parents.
• Flexible Working: Hybrid working options (e.g., from our London or Oxford office).
• Inclusive Time Off: 'Bank Your Bank Holiday' program allows exchanging public holidays for dates of personal or cultural significance.
• Vibrant Social Culture: Regular Town Halls, team picnics, organized sports events, and frequent opportunities to connect.
• Green Commute: Cycle-to-Work scheme and offices near major transport hubs.