Late-Stage LNP Process Development Scientist

About the role

The Late-Stage LNP Process Development team at Eurofins Professional Scientific Services focuses on supporting the process development, scale-up, and characterization of LNP clinical stage drug products. This role involves refining process controls and improving process understanding for multiple programs at various stages of clinical development.

Responsibilities

• Support routine process development and process characterization activities centered around the LNP drug product manufacturing process.
• Execute routine analytics including dynamic light scattering (DLS), UV-quantification via Ribogreen®, pH, and osmolality for in-process monitoring.
• Perform experiments under limited to no supervision under subject matter expert guidance.
• Organize and analyze data, interpret results, and present findings within the process development team and cross-functionally.
• Author technical documentation (SOPs, reports, protocols) as required.
• Document experiments and protocols using electronic lab notebooks (e.g., Benchling).
• Maintain laboratory equipment, order critical reagents, and support operational excellence activities.

Requirements

• B.S. degree in chemical/biomedical engineering, chemistry, or biological sciences (or related field) with 3-4 years of relevant laboratory experience.
• M.S. degree in biological or biochemical sciences (or related field) with 1-2 years of relevant laboratory experience.
• Proficiency in bench-scale drug product manufacturing of LNPs with a focus on mixing and tangential flow filtration (TFF) processes.
• Experience with practices and equipment used in process development of nucleic acids (experience with T-mixing and TFF is preferred).
• Experience with DLS and osmolality for in-process monitoring.
• Experience working with ELN systems such as Benchling.
• Experience with technical documentation (SOPs, technical reports, protocols).
• Ability to follow established SOPs for routine analytics.
• Ability to achieve results, keep to a timeline, and find solutions to ensure that overall project deliverables are met.
• Strong attention to detail, analysis of data/reports, troubleshooting, and problem-solving abilities.
• Strong writing and communication skills with the ability to understand and communicate scientific information.
• Strong organizational and time management skills.
• Willingness to collaborate with cross-functional teams.
• Proactive, creative, and positive attitude.

Qualifications

• B.S. degree in chemical/biomedical engineering, chemistry, or biological sciences (or related field) with 3-4 years of relevant laboratory experience.
• M.S. degree in biological or biochemical sciences (or related field) with 1-2 years of relevant laboratory experience.
• Experience with LNP process development, tech transfer, and GMP manufacturing (plus experience with T-mixing and TFF is preferred).
• Experience with DLS and osmolality for in-process monitoring.
• Experience with UV-quantification via Ribogreen®.
• Experience with ELN systems such as Benchling.
• Experience with technical documentation (SOPs, technical reports, protocols).
• Ability to follow established SOPs for routine analytics.
• Ability to achieve results, keep to a timeline, and find solutions to ensure that overall project deliverables are met.
• Strong attention to detail, analysis of data/reports, troubleshooting, and problem-solving abilities.
• Strong writing and communication skills with the ability to understand and communicate scientific information.
• Strong organizational and time management skills.
• Willingness to collaborate with cross-functional teams.
• Proactive, creative, and positive attitude.

Skills

• Experience with LNP process development, tech transfer, and GMP manufacturing.
• Experience with DLS and osmolality for in-process monitoring.
• Experience with UV-quantification via Ribogreen®.
• Experience with ELN systems such as Benchling.
• Experience with technical documentation (SOPs, technical reports, protocols).
• Ability to follow established SOPs for routine analytics.
• Ability to achieve results, keep to a timeline, and find solutions to ensure that overall project deliverables are met.
• Strong attention to detail, analysis of data/reports, troubleshooting, and problem-solving abilities.
• Strong writing and communication skills with the ability to understand and communicate scientific information.
• Strong organizational and time management skills.
• Willingness to collaborate with cross-functional teams.
• Proactive, creative, and positive attitude.

Benefits

• Comprehensive medical coverage, dental, and vision options.
• Life and disability insurance.
• 401(k) with company match.
• Paid vacation and holidays.
• Eligibility for yearly goal-based bonus & merit-based increases.

Pay

$36.00 - $41.00 per hour

Schedule

Full-time, Monday-Friday, 8am-5pm with overtime as needed.