Isotope Labeling Chemist- Associate Technical Professional

About the role

We are seeking a highly motivated Technical Professional (TP) to support the synthesis, characterization, and deployment of isotope-labeled molecules, including deuterated and other isotopically enriched compounds, for neutron scattering and nanoscience research.

Responsibilities

• Design, synthesize, purify, and scale deuterated and other isotopically labeled molecules to support neutron scattering, nanoscience, and materials research programs.
• Characterize isotope-labeled compounds using advanced analytical techniques and maintain high standards of data quality, documentation, and reproducibility.
• Collaborate with scientists, technical staff, and external users across the Center for Nanophase Materials Sciences and the Neutron Scattering Division to develop materials and samples that enable high-impact scientific research.
• Operate, maintain, and troubleshoot synthetic and analytical instrumentation; develop and implement laboratory procedures that ensure reliable and efficient facility operations.
• Train and mentor staff, users, students, and visiting researchers in the safe and effective use of synthetic chemistry laboratories, analytical instrumentation, and associated research methodologies.
• Contribute to scientific publications, technical reports, user proposals, and presentations by effectively communicating research results and collaborating within multidisciplinary scientific teams.
• Support user projects, thematic research efforts, and strategic scientific campaigns by delivering high-quality technical expertise, samples, and research outcomes on schedule.
• Ensure compliance with all environmental, safety, health, security, quality assurance, and operational requirements while promoting a strong culture of laboratory safety and continuous improvement.
• Demonstrate a commitment to ORNL’s core values of Impact, Integrity, Teamwork, Safety, and Service through professional conduct, scientific excellence, and effective collaboration.

Qualifications

• A bachelor’s degree in Organic Chemistry, Polymer Chemistry, Materials Science, or a closely related field
• A minimum of 2 years of demonstrated experience in organic synthesis and molecular characterization techniques
• A Ph.D. in Organic Chemistry, Polymer Chemistry, Materials Science, or a closely related field preferred
• Experience in the synthesis and purification of deuterated lipids, deuterated sterols, and deuterated organic solvents (low boiling point) is considered a strong advantage
• Expertise in multi-step organic synthesis, including monomer synthesis, biomolecule synthesis, and functional material synthesis
• Experience in the design and synthesis of isotope-labeled molecules, particularly deuterated compounds
• Familiarity with scale-up synthesis, air- and moisture-sensitive reactions, and isotopic purity analysis is considered a strong advantage
• Hands-on experience with analytical and characterization techniques such as NMR, IR, LC-MS, and GC-MS for complex organic molecules, especially isotope-labeled systems
• Excellent written and oral communication skills, including a strong publication record
• A highly motivated self-starter with the ability to work independently and contribute creatively within multidisciplinary collaborative teams
• Ability to thrive in a fast-paced research environment, manage multiple priorities, and adapt to evolving project needs