Isotope Manufacturing Scientist

About the role

The Isotope Manufacturing Scientist will support the development, scale-up, and implementation of isotope manufacturing technologies at Perspective's new radiopharmaceutical manufacturing facility. This role combines applied scientific expertise with hands-on operational execution, ensuring that isotope processing activities are translated into reliable daily operations aligned with the facility's technical and regulatory requirements.

Responsibilities

• Lead and execute hands-on isotope production process development, including radioisotope separations within a hot cell environment
• Facilitate the transfer and scaling of R&D processes into standardized routine operations
• Conduct operations within hot cells using remote manipulators
• Handle alpha-, beta-, and gamma-emitting materials in accordance with radiation safety requirements and ALARA principles
• Support the development of procedures, experimental protocols, development reports, batch records, and documents supporting regulatory submissions
• Perform basic equipment troubleshooting and support preventive and corrective maintenance
• Perform analytical testing (e.g., gamma spectroscopy, alpha spectroscopy, dose calibration) to evaluate isotope product activity, purity, yield, and process performance
• Perform chemical laboratory operations including safe acid handling, precise weighing and solution preparation, and general laboratory safety practices
• Train, mentor, and support production staff on radiochemical processes, hot cell operations, GMP expectations, and safety protocols
• Serve as a technical resource for isotope manufacturing and radiopharmaceutical processing, providing execution-level support for continuous improvement initiatives
• Support facility planning and equipment integration for radioisotope development and production by providing hands-on operational input and testing support
• Contribute to isotope scale-up initiatives, QA/QC processes, and supply chain coordination through execution, troubleshooting, and data generation

Requirements

• Bachelor’s, Master’s, or PhD degree in Chemistry, Chemical Engineering, Radiochemistry, or related field
• 3-5+ years of experience in radiochemistry, radiopharmaceutical, isotope manufacturing, or cGMP manufacturing environments
• Hands-on experience working in hot cells, shielded environments, or with radioactive materials

Skills & Abilities

• Strong skills to perform chemical operations in a hot cell environment using remote manipulations
• Deep understanding of radiochemical processes, metrology, and separation chemistry
• In-depth knowledge of safety requirements, including radiation safety, ALARA principles, contamination control, chemical compatibility, and hazardous material handling
• Excellent communication skills, the ability to clearly document executional observations and processes
• Demonstrated ability to execute and refine defined processes for scaled manufacturing
• Familiarity with cGMP, FDA, NRC, and other applicable regulatory frameworks
• Comfortable working in a fast-paced, cross-disciplinary environment
• Ability to work in a rapidly changing environment
• Proficient with Microsoft Office platforms