Immunoassay Biomarker Scientist

About the role

This position supports a Neuroscience Biomarkers client team responsible for immunoassay-based methods to identify and quantify biomarkers associated with neurodegenerative diseases, including Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis. We are seeking a motivated scientist eager to gain hands-on experience in immunoassay workflows applied to serum, plasma, CSF, sample lysate, and tissue biomarker studies, and to grow their technical skills in a collaborative, fast-moving research environment.

Responsibilities

• Perform analyses as part of the development and validation of novel immunoassay-based biomarker methods, as well as applications of these methods for clinical trials in neurodegenerative diseases, including Alzheimer’s, Parkinson’s, ALS, and rare brain disorders.
• Work with project team leads and other associates to perform experiments supporting both preclinical and clinical characterization and evaluation of therapeutic molecules through biomarker assay development.
• Assist with the planning and execution of immunoassay method developments, method optimization and validation, as well as sample analyses from different preclinical sample sets and clinical cohorts.
• Work directly on-site with methods in the laboratory, summarizing and reporting method status and results for internal partners.
• Implement assay validation procedures to deliver high-performance biomarker assays for preclinical and clinical sample analyses.

Requirements

• B.S. in Biology, Chemistry, Biochemistry, or related life sciences field with at least 3 years of relevant industry experience utilizing ELISA and MSD.
• Strong understanding of the principles for immunoassays (e.g., antibodies and other ligand-based molecules, assay design), protein biomarker quantification, and assay validation.
• Hands-on experience in protein biomarker applications (e.g., clinical diagnostics, clinical trials, or preclinical sample analysis).
• Experience working with human or animal specimens (tissue and biofluids such as plasma, serum, and CSF) under BSL-2 or equivalent safety conditions.

Preferred Qualifications

• Experience with clinical sample analysis using immunoassay methods.
• Additional experience with qualitative (e.g., electrophoresis techniques, Western blot) and quantitative (e.g., Ella, Simoa, NULISA, SpearBio) immunoassay-based analyses.
• Experience with Good Laboratory Practices (GLP), Clinical Laboratory Standards Institute (CLSI), and/or Clinical Laboratory Improvement Amendments (CLIA) validation standards.
• Authorization to work in the United States indefinitely without restriction or sponsorship.

Benefits

• Comprehensive medical coverage, dental, and vision options.
• Life and disability insurance.
• 401(k) with company match.
• Paid vacation and holidays.
• Eligibility for yearly goal-based bonus and merit-based increases.

Pay

$36.00-$41.00 per hour based on education and related experience.

Schedule

Full-time, Monday-Friday, 8am-5pm with overtime as needed.

Candidates living within a commutable distance of Boston, MA are encouraged to apply.