Group Leader, Immunology

The Team

Our immune cell reprogramming team integrates foundational research on immunology and disease biology with AI-modeling to develop engineered cells that harness our own immune system to detect and treat early signs of age-related diseases, like cancer, Alzheimer’s, and Parkinson’s. These technologies will enable precise, context-dependent therapeutic responses only when and where it is needed.

Vision

• Pursue large scientific challenges that cannot be pursued in conventional environments
• Enable individual investigators to pursue their riskiest and most innovative ideas
• Facilitate research by scientists and clinicians at our home institutions and beyond

The Opportunity

The Biohub invites exceptional scientists to apply for a Group Leader (Principal Investigator-equivalent) position. We seek researchers who pursue fundamental questions in immunology, including—though not limited to—experts in systems immunology, immune engineering, and functional or molecular immunology, with a particular emphasis on cellular subtypes associated with immune regulation in cancer and/or neuroinflammation. Ideal candidates will aim to uncover the core principles and dynamic behaviors that govern immune system function in both health and disease. We especially welcome applicants who integrate quantitative, high-throughput, and systems approaches to address broad immunological questions and principles, rather than those focused primarily on tool or method development. The overarching mission is to reveal the fundamental principles governing the function and development of the human immune system, including via regulatory, signaling, and cell-cell molecular interaction network analysis. The goal will be to identify mechanisms that can help reprogram the immune system’s function to monitor organ specific health conditions, modulate cell trafficking, and restore normal immune function in human disease conditions.

What You'll Do

• Lead an innovative, rigorous, and highly collaborative research program aligned with the mission of Biohub, focused on advancing fundamental understanding of the immune system.
• Develop a transformative research vision and provide technical guidance and mentorship to team members.
• Play a key role in our collaborative efforts to engineer immune cells to detect, prevent, and cure organ-specific diseased states by leveraging your expertise in immunology.
• Engage with colleagues throughout the Biohub to uphold our values of scholarly excellence, innovation, open communication, collaboration, partnership, and opportunity.
• Communicate progress and results with colleagues and the leadership team.
• Publish and disseminate impactful findings and the products of your research as preprints (medRxiv, bioRxiv) and/or software repositories (e.g., GitHub).
• Collaborate with the Biohub team to patent and license technologies resulting from your research.

What You'll Bring

• PhD or MD or equivalent degree in immunology or a related field.
• A minimum of 5 years post-doctoral experience with a strong foundation in immunology.
• An innovative research plan aimed at revealing the fundamental principles that govern the immune system.
• Demonstrated publication track record in top tier journals on topics related to the scientific goals of this position.
• Demonstrated leadership, track record of innovation, and ability to work collaboratively.
• Supervisory or mentoring experience is a plus but not required for early-career applicants, but expected for more senior candidates.
• Demonstrating a creative vision to establish a highly innovative and impactful research program.
• Outstanding interpersonal and communication skills.
• Demonstrated commitment to open science and highly aligned with the mission and values of Biohub.

Compensation

The New York City, NY base pay range for a new hire in this role is $153,000.00 - $185,000.00. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.

Better Together

• We’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager's discretion and communicated during the interview process.
• We offer a wide range of benefits to support the people who make all we do possible, including:
• Provides a generous employer match on employee 401(k) contributions to support planning for the future.
• Paid time off to volunteer at an organization of your choice.
• Funding for select family-forming benefits.
• Relocation support for employees who need assistance moving.