Genomic Instability and Cancer Genetics – Tenure Track (Assistant/Associate)

About the role

The Genomic Instability and Cancer Genetics (GICG) Research Program at Rutgers Cancer Institute seeks outstanding investigators focused on the mechanisms of genomic instability, cancer genome evolution, and their translation into clinical applications. Faculty appointments are available at the Assistant or Associate Professor level, tenure‑track or tenured depending on qualifications and experience. The program investigates how genomic instability arises, how defects in genome maintenance pathways drive tumor initiation and progression, and how perturbations influence tumor response to treatment, with a key effort on leveraging mechanism‑based genomic and molecular markers to identify therapeutic vulnerabilities. Research areas span DNA repair and replication fidelity, chromosome segregation, cancer genome evolution, and gene expression and tissue homeostasis programs that shape tumor development and therapeutic response. Investigators integrate mechanistic, computational, and translational approaches to define how genome instability drives cancer and to exploit these vulnerabilities for therapeutic intervention. Candidates pursuing basic, translational, or preclinical research in cancer genetics and genomics using cutting‑edge approaches are encouraged, with particular interest in mechanisms of genomic instability and DNA repair dysfunction, therapeutic vulnerabilities associated with altered cancer genomes, molecular and cellular mechanisms of radiation and genotoxic response, co‑adaptation between the tumor microenvironment and evolving cancer cells, and the genetics of cancer predisposition syndromes. Successful candidates will establish or contribute to an innovative, independent, and collaborative research program addressing fundamental questions in cancer biology and genomic instability, and