Force Field Developer at D. E. Shaw Research

About the Role

D. E. Shaw Research is seeking scientists with expertise in force field development to join our New York–based team. This is a unique opportunity to develop and work with transformative technology in a dynamic, interdisciplinary environment.

Relevant areas of experience might include development of physics-based force fields, application of machine learning approaches to force-field development, development of novel parameterization strategies, ligand and small molecule parameterization, and force field validation and verification.

Successful candidates will contribute to the development of more accurate force fields for biomolecular simulation and drug discovery.

Requirements

• Ph.D. in chemistry, chemical physics, computational chemistry, biophysics, or a related field.
• Strong research skills and a record of innovation and accomplishment.
• Strong understanding of physics and/or machine learning combined with knowledge of chemistry.
• Excellent communication skills to facilitate collaboration with our drug discovery team.

Specific knowledge of any particular area is less critical than the above qualifications.

About D. E. Shaw Research

D. E. Shaw Research (DESRES), based in New York City, develops and uses advanced computational technologies to understand the behavior of biologically and pharmaceutically significant molecules at an atomic level of detail, and to design precisely targeted, highly selective drugs for the treatment of various diseases.

Among its core technologies is Anton, a proprietary special-purpose supercomputer that DESRES designed and constructed to vastly accelerate the process of molecular dynamics simulation. DESRES uses Anton machines and high-speed commodity hardware, together with machine learning methods and other computational techniques, in both internal and collaborative drug discovery programs.

We are looking to add innovative contributors who share our commitment to fostering a stimulating, positive, and collaborative work environment.

Pay

The expected annual base salary for this position is $260,000–$400,000. The applicable annual base salary paid to a successful applicant will be determined based on multiple factors, including the nature and extent of prior experience and educational background.

Our compensation package also includes variable compensation in the form of sign-on and year-end bonuses.

Benefits

• Generous benefits, including relocation and immigration assistance.

Schedule

We follow a hybrid work schedule, in which employees work from the office on Tuesday through Thursday and have the option of working from home on Monday and Friday.