Force Field Developer at D. E. Shaw Research
About the role
D. E. Shaw Research is seeking scientists with expertise in force field development to join our New York–based team. This is a unique opportunity to develop and work with transformative technology in a dynamic, interdisciplinary environment. D. E. Shaw Research (DESRES), based in New York City, develops and uses advanced computational technologies to understand the behavior of biologically and pharmaceutically significant molecules at an atomic level of detail, and to design precisely targeted, highly selective drugs for the treatment of various diseases. Among its core technologies is Anton, a proprietary special-purpose supercomputer that DESRES designed and constructed to vastly accelerate the process of molecular dynamics simulation. DESRES uses Anton machines and high-speed commodity hardware, together with machine learning methods and other computational techniques, in both internal and collaborative drug discovery programs. We are looking to add innovative contributors who share our commitment to fostering a stimulating, positive, and collaborative work environment.
Responsibilities
- Develop physics-based force fields
- Apply machine learning approaches to force‑field development
- Develop novel parameterization strategies
- Perform ligand and small molecule parameterization
- Conduct