FDA Research Opportunity- Bacteriophage Therapy as a Preventative of Menstrual Toxic Shock Syndrome (mTSS) Caused by Staphylococcus aureus

About the role

The National Center for Toxicological Research (NCTR) at the FDA seeks a researcher to study bacteriophages and endolysins as potential treatments for menstrual toxic shock syndrome (mTSS) caused by Staphylococcus aureus. The project involves analyzing vaginal microbiome data, testing phage and endolysin stability and activity, and assessing their effectiveness in in vitro models.

Responsibilities

• Isolate, purify, and characterize S. aureus bacteriophages
• Test phage and endolysin preparations in vaginal tract models
• Investigate the effectiveness of bacteriophage-derived endolysins
• Conduct molecular biology experiments to isolate and express endolysins
• Present findings at national microbiology meetings

Requirements

This position requires a bachelor's or master's degree in relevant fields such as Chemistry and Materials Sciences, Communications and Graphics Design, Computer, Information, and Data Sciences, Earth and Geosciences, Engineering, Environmental and Marine Sciences, Life Health and Medical Sciences, Mathematics and Statistics, Physics, Science & Engineering-related, or Social and Behavioral Sciences. U.S. citizenship or permanent residency is required, with preference given to candidates who have lived in the U.S. for at least 36 out of the past 60 months.

Qualifications

The ideal candidate should have foundational knowledge in microbiology, particularly bacteriology related to Staphylococcus aureus and its bacteriophages. Prior experience in molecular biology and laboratory techniques is preferred.

Skills

Strong skills in molecular biology, laboratory techniques, and data analysis are essential. Proficiency in bioinformatics and experience with vaginal microbiome analysis is desirable.

Benefits

The participant will receive a monthly stipend commensurate with educational level and experience. Proof of health insurance is required.

Pay

The stipend amount is commensurate with the participant's educational level and experience.

Schedule

The appointment will initially be for one year, but may be renewed upon recommendation of FDA and is contingent on the availability of funds.

Contact

If you have questions, send an email to ORISE.FDA.NCTR@orau.org. Please include the reference code for this opportunity in your email.