Expert Pharma Discovery Biologist
Cogent Scientific · South San Francisco, CA · 1 mo ago
On-siteResearchFull-time
Job Duties
- Leading in vitro discovery biology across oncology programs, from early target validation through candidate selection, spanning multiple therapeutic modalities.
- Contributing to target identification and prioritization by integrating literature, pathway biology, and emerging clinical and preclinical data to nominate and validate novel therapeutic targets.
- Designing and executing cell-based assays to evaluate compound activity, including viability, proliferation, and apoptosis readouts across relevant tumor models.
- Driving mechanistic and signaling studies (e.g., Western blot, phosphoproteomics, pathway analysis) to characterize target engagement and mechanism of action.
- Leading target biology efforts including evaluation of target expression, antigen density, receptor internalization, intracellular trafficking, and target-dependent processing.
- Developing and optimizing disease-relevant in vitro models (e.g., 3D culture systems, model generation, co-culture platforms) to characterize novel modalities and enable translational studies.
Job Requirements
- An MS in Molecular Biology, Biochemistry or a related field with 6-8 years of industry experience in oncology drug discovery or targeted therapeutics research.
- Excellent communication skills – verbal and written.
- Works well both within a team and as an individual.
- Demonstration of excellent team player and collaboration skills, very strong attention to detail, very strong problem-solving skills, a high level of learning agility, and the ability to work across functions.
- The ideal candidate will be enthusiastic and self-motivated, with the leadership and communication skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal delivery.
Pay
Competitive pay is offered.
Schedule
This is a day shift position (approx. 8a-5p local time).
Benefits
- Medical/dental/vision insurance
- 401(k)
- Parenthood leave
- PTO and paid holidays
Core Values
- Client Focused: We only succeed when our clients succeed.
- Outstanding: We deliver meticulous results through outstanding performance.
- Good: We act ethically and morally.
- Employee-Centric: We honor and support our employees.
- Nimble: We are prepared to adapt in an ever-changing industry.
- Team-Oriented: We collaborate with each other and with our clients.