Jobs · Research · California

Expert Pharma Discovery Biologist

Cogent Scientific · South San Francisco, CA · 1 mo ago
On-siteResearchFull-time

Job Duties

  • Leading in vitro discovery biology across oncology programs, from early target validation through candidate selection, spanning multiple therapeutic modalities.
  • Contributing to target identification and prioritization by integrating literature, pathway biology, and emerging clinical and preclinical data to nominate and validate novel therapeutic targets.
  • Designing and executing cell-based assays to evaluate compound activity, including viability, proliferation, and apoptosis readouts across relevant tumor models.
  • Driving mechanistic and signaling studies (e.g., Western blot, phosphoproteomics, pathway analysis) to characterize target engagement and mechanism of action.
  • Leading target biology efforts including evaluation of target expression, antigen density, receptor internalization, intracellular trafficking, and target-dependent processing.
  • Developing and optimizing disease-relevant in vitro models (e.g., 3D culture systems, model generation, co-culture platforms) to characterize novel modalities and enable translational studies.

Job Requirements

  • An MS in Molecular Biology, Biochemistry or a related field with 6-8 years of industry experience in oncology drug discovery or targeted therapeutics research.
  • Excellent communication skills – verbal and written.
  • Works well both within a team and as an individual.
  • Demonstration of excellent team player and collaboration skills, very strong attention to detail, very strong problem-solving skills, a high level of learning agility, and the ability to work across functions.
  • The ideal candidate will be enthusiastic and self-motivated, with the leadership and communication skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal delivery.

Pay

Competitive pay is offered.

Schedule

This is a day shift position (approx. 8a-5p local time).

Benefits

  • Medical/dental/vision insurance
  • 401(k)
  • Parenthood leave
  • PTO and paid holidays

Core Values

  • Client Focused: We only succeed when our clients succeed.
  • Outstanding: We deliver meticulous results through outstanding performance.
  • Good: We act ethically and morally.
  • Employee-Centric: We honor and support our employees.
  • Nimble: We are prepared to adapt in an ever-changing industry.
  • Team-Oriented: We collaborate with each other and with our clients.

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